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Reactive Group Datasheet


What are reactive groups?

Reactive groups are categories of chemicals that typically react in similar ways because they are similar in their chemical structure. Each substance with a chemical datasheet has been assigned to one or more reactive groups, and CAMEO Chemicals uses the reactive group assignments to make its reactivity predictions. More info about reactivity predictions...

If you can't find a chemical in the database--but you know what reactive group it belongs in--you can add the reactive group to MyChemicals instead in order to see the reactivity predictions.

There are 186 chemical datasheets assigned to this reactive group.


Many low-molecular-weight ketones (such as acetone and methyl ethyl ketone) are highly flammable. Most ketones are liquids with relatively high vapor pressures, capable of forming explosive mixtures with air.
Materials in this group are reactive with many acids and bases liberating heat and flammable gases (e.g., H2 from NaH). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with HNO3, HNO3 + H2O2, and HClO4.
Varies very widely. Some ketones are highly volatile and may have narcotic or anesthetic effects. Entry into the body occurs by absorption through the skin as well as inhalation and ingestion.
Other Characteristics
Compounds in this group are characterized by a carbonyl attached to two organic groups. These groups may be alkyl (paraffins) or aryl (aromatic). Reactions of this group are very similar in their behavior to that of aldehydes, because of their similar structure. These materials are generally used as solvents in the paint, textiles, plastics, and lacquer industries.
2-tridecanone, acetone, acetophenone, benzoin, cyclohexanone, isophorone, methyl acetone, methyl amyl ketone, methyl butanone, methyl ethyl ketone, ninhydrin.

Reactivity Documentation

Use the links below to find out how this reactive group interacts with any of the reactive groups in the database.

The predicted hazards and gas byproducts for each reactive group pair will be displayed, as well as documentation and references that were used to make the reactivity predictions.

Mix Ketones with: