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Reactive Group Datasheet


What are reactive groups?

Reactive groups are categories of chemicals that typically react in similar ways because they are similar in their chemical structure. Each substance with a chemical datasheet has been assigned to one or more reactive groups, and CAMEO Chemicals uses the reactive group assignments to make its reactivity predictions. More info about reactivity predictions...

If you can't find a chemical in the database--but you know what reactive group it belongs in--you can add the reactive group to MyChemicals instead in order to see the reactivity predictions.

There are 21 chemical datasheets assigned to this reactive group.


Not highly flammable, but may be combustible.
Oximes behave as weak acids and bases. Aldoximes can peroxidize and explode during distillation. In the presence of even trace amounts of acid, ketoximes can undergo an exothermic acid-catalyzed rearrangement called the Beckmann rearrangement. The product of the rearrangement is a stable amide; however, the reaction can be exothermic enough to cause the explosion of unreacted starting material. The presence of acidic salts significantly lowers the temperature required for this explosion. The hydrolysis of oximes proceeds easily by heating in the presence of various inorganic acids, and the oximes decompose into the corresponding ketones or aldehydes, and hydroxylamines. Oximes may decompose upon heating, resulting in an explosive event.
Some may be very toxic. For example, aldicarb oxime, the hydrolysis product of the carbamate ester pesticide aldidarb, can have nervous system effects.
Other Characteristics
Compounds containing a C=N-O-R structure. They can be produced by the condensation of aldehydes or ketones with hydroxylamines. Oximes derived from aldehydes have at least one hydrogen atom on the C=N carbon atom, and are called aldoximes. Oximes derived from ketones do not have any hydrogen atoms on the C=N carbon, and they are called ketoximes. Aldoximes tend to be more reactive than ketoximes. Oximes are found in some pesticides (as oxime carbamates) and in some pharmaceutical compounds. The largest industrial use for oximes is as an intermediate in the industrial production of caprolactam, a precursor to Nylon 6.
Aldicarb oxime, dimethyl glyoxime, methoxime.

Reactivity Documentation

Use the links below to find out how this reactive group interacts with any of the reactive groups in the database.

The predicted hazards and gas byproducts for each reactive group pair will be displayed, as well as documentation and references that were used to make the reactivity predictions.

Mix Oximes with: