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Chemical Datasheet


2.1 - Flammable gas
Chemical Identifiers | Hazards | Response Recommendations | Physical Properties | Regulatory Information | Alternate Chemical Names

Chemical Identifiers

The Chemical Identifier fields include common identification numbers, the NFPA diamond, U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources..
CAS Number UN/NA Number DOT Hazard Label USCG CHRIS Code
  • 75-50-3   (TRIMETHYLAMINE)
  • Flammable Gas
NFPA 704
Diamond Hazard Value Description
3 0
Blue Health 3 Can cause serious or permanent injury.
Red Flammability 4 Burns readily. Rapidly or completely vaporizes at atmospheric pressure and normal ambient temperature.
Yellow Instability 0 Normally stable, even under fire conditions.
White Special
(NFPA, 2010)
NIOSH Pocket Guide International Chem Safety Card
General Description
A colorless gas with a fishlike odor at low concentrations changing to ammonia-like odor at higher concentrations. Shipped as a liquid under its own vapor pressure. Contact with the unconfined liquid can cause frostbite from evaporative cooling or chemical type burns. The gasis corrosive and dissolves in water to form flammable, corrosive solutions. Gas is an asphyxiate by the displacement of air. Produces toxic oxides of nitrogen during combustion. Prolonged exposure to heat can cause the containers to rupture violently and rocket. Long-term inhalation of low concentrations or short -term inhalation of high concentrations has adverse health effects.


The Hazard fields include special hazard alerts, air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
Air & Water Reactions
Highly flammable and easily ignited. Water soluble.
Fire Hazard
FLAMMABLE. Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area. Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back. (USCG, 1999)
Health Hazard
VAPOR: POISONOUS IF INHALED. Irritating to eyes, nose, and throat. LIQUID: Will burn skin and eyes. Harmful if swallowed. (USCG, 1999)
Reactivity Profile
TRIMETHYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Contamination of an ethylene oxide tank with trimethylamine caused an explosion [BCISC Quart. Safety Summ., 1966, 37, 44].
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below. More info about absorbents, including situations to watch out for...

Response Recommendations

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 118 [Gases - Flammable - Corrosive]:

As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 800 meters (1/2 mile).

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions. (ERG, 2016)
Excerpt from ERG Guide 118 [Gases - Flammable - Corrosive]:


SMALL FIRE: Dry chemical or CO2.

LARGE FIRE: Water spray, fog or regular foam. Move containers from fire area if you can do it without risk. Damaged cylinders should be handled only by specialists.

FIRE INVOLVING TANKS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety devices; icing may occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
Non-Fire Response
Excerpt from ERG Guide 118 [Gases - Flammable - Corrosive]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. Do not touch or walk through spilled material. Stop leak if you can do it without risk. If possible, turn leaking containers so that gas escapes rather than liquid. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Do not direct water at spill or source of leak. Isolate area until gas has dispersed. (ERG, 2016)
Protective Clothing
Wear goggles and self-contained breathing apparatus. (USCG, 1999)
DuPont Tychem® Suit Fabrics
Tychem® Fabric Legend
QC = Tychem QC
SL = Tychem SL
TF = Tychem F
TP = Tychem ThermoPro
C3 = Tychem CPF 3
BR = Tychem BR
RC = Tychem Responder® CSM
TK = Tychem TK
RF = Tychem Reflector®
Testing Details
Permeation data obtained per ASTM F739. Normalized breakthrough times (the time at which the permeation rate is equal to 0.1 µg/cm2/min) reported in minutes. All liquid chemicals have been tested between approximately 20°C and 27°C unless otherwise stated. All chemicals have been tested at a concentration of greater than 95% unless otherwise stated. Chemical warfare agents (Lewisite, Sarin, Soman, Sulfur Mustard, Tabun and VX Nerve Agent) have been tested at 22°C and 50% relative humidity per military standard MIL-STD-282.
Normalized Breakthrough Times (in Minutes)
Chemical CAS Number State QC SL TF TP C3 BR RC TK RF
Trimethylamine (gas) 75-50-3 Vapor >480
> indicates greater than.
A blank cell indicates the fabric has not been tested. The fabric may or may not offer barrier.

Special Warnings from DuPont

  1. Serged and bound seams are degraded by some hazardous liquid chemicals, such as strong acids, and should not be worn when these chemicals are present.
  2. CAUTION: This information is based upon technical data that DuPont believes to be reliable. It is subject to revision as additional knowledge and experience are gained. DuPont makes no guarantee of results and assumes no obligation or liability...
    ... in connection with this information. It is the user's responsibility to determine the level of toxicity and the proper personal protective equipment needed. The information set forth herein reflects laboratory performance of fabrics, not complete garments, under controlled conditions. It is intended for informational use by persons having technical skill for evaluation under their specific end-use conditions, at their own discretion and risk. Anyone intending to use this information should first verify that the garment selected is suitable for the intended use. In many cases, seams and closures have shorter breakthrough times and higher permeation rates than the fabric. Please contact DuPont for specific data. If fabric becomes torn, abraded or punctured, or if seams or closures fail, or if attached gloves, visors, etc. are damaged, end user should discontinue use of garment to avoid potential exposure to chemical. Since conditions of use are outside our control, we make no warranties, express or implied, including, without limitation, no warranties of merchantability or fitness for a particular use and assume no liability in connection with any use of this information. This information is not intended as a license to operate under or a recommendation to infringe any patent or technical information of DuPont or others covering any material or its use.

(DuPont, 2016)

First Aid
INHALATION: remove victim to fresh air and call a doctor; give artificial respiration and oxygen if needed.

EYES: flush with water for at least 15 minutes; consult an eye doctor.

SKIN: flush with water, wash with soap and water. (USCG, 1999)

Physical Properties

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds. The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C3H9N
Flash Point: Not Applicable. Gas. (USCG, 1999)
Lower Explosive Limit (LEL): 2 % (USCG, 1999)
Upper Explosive Limit (UEL): 11.6 % (USCG, 1999)
Autoignition Temperature: 374 ° F (USCG, 1999)
Melting Point: -178.8 ° F (USCG, 1999)
Vapor Pressure: 1487.83 mm Hg at 70 ° F (USCG, 1999)
Vapor Density (Relative to Air): 2 (USCG, 1999)
Specific Gravity: 0.633 at 68 ° F (USCG, 1999)
Boiling Point: 37.2 ° F at 760 mm Hg (USCG, 1999)
Molecular Weight: 59.11 (USCG, 1999)
Water Solubility: data unavailable
Ionization Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

Interim AEGLs for Trimethyl amine (75-50-3)
Exposure Period AEGL-1 AEGL-2 AEGL-3
10 minutes 8 ppm 240 ppm 750 ppm
30 minutes 8 ppm 150 ppm 490 ppm
60 minutes 8 ppm 120 ppm 380 ppm
4 hours 8 ppm 67 ppm 220 ppm
8 hours 8 ppm 51 ppm 170 ppm
Level of Distinct Odor Awareness = 0.00051 ppm
(NAC/NRC, 2016)

ERPGs (Emergency Response Planning Guidelines)

Chemical ERPG-1 ERPG-2 ERPG-3
Trimethylamine (75-50-3) 0.1 ppm star-in-circle icon indicates that odor should be detectable near ERPG-1. 100 ppm 500 ppm
star-in-circle icon indicates that odor should be detectable near ERPG-1.
(AIHA, 2016)

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Trimethylamine (75-50-3) 8 ppm 120 ppm 380 ppm LEL = 20000 ppm
(DOE, 2016)

Regulatory Information

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists and the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
CAA 112(r)
Methanamine, N,N-dimethyl- 75-50-3 100 pounds 10000 pounds
Trimethylamine 75-50-3 100 pounds 10000 pounds

(EPA List of Lists, 2015)

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

Chemical of Interest CAS Number Min Conc STQ Security
Min Conc STQ Security
Min Conc STQ Security
Trimethylamine; [Methanamine, N,N-dimethyl-] 75-50-3 1.00 % 10000 pounds flammable

(DHS, 2007)

Alternate Chemical Names

This section provides a listing of alternate names for this chemical, including trade names and synonyms.