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Chemical Datasheet

ETHYLBIS(2-CHLOROETHYL)AMINE

6.1 - Poison
Chemical Identifiers | Hazards | Response Recommendations | Physical Properties | Regulatory Information | Alternate Chemical Names

Chemical Identifiers

The Chemical Identifier fields include common identification numbers, the NFPA diamond, U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources..
CAS Number UN/NA Number DOT Hazard Label USCG CHRIS Code
  • 538-07-8
  • Poison
none
NFPA 704
data unavailable
NIOSH Pocket Guide International Chem Safety Card
none
General Description
Dark liquid with a faint, fishy amine odor. Used as a delayed-action, military casualty agent.

Hazards

The Hazard fields include special hazard alerts, air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
When dissolved in water, it is a strong base.
Fire Hazard
When heated to decomposition, it emits very toxic fumes of nitrogen oxides and chlorides. Polymerizes slowly. (Hazard not specified.) (EPA, 1998)
Health Hazard
This compound is a nitrogen mustard. It is highly irritating to skin, eyes, and mucous membranes. Nitrogen mustards have preferential toxicity for rapidly dividing cells. Workers exposed briefly to estimated concentrations of 10-100 ppm by inhalation became severely ill. The median lethal dosage is 1,500 mg-minute/m3. (EPA, 1998)
Reactivity Profile
When dissolved in water, ETHYLBIS(2-CHLOROETHYL)AMINE is a strong base; reacts violently with strong oxidants and acids ; attacks copper and copper compounds. [Handling Chemicals Safely 1980. p. 123]; reacts with hypochlorites to give N-chloroamines, some of which, are explosives when isolated [Bretherick 1979 p. 108].
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below. More info about absorbents, including situations to watch out for...

Response Recommendations

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: If this material is being used as a weapon, see ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 2810 datasheet. Otherwise increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Firefighting
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

SMALL FIRE: Dry chemical, CO2 or water spray.

LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
Non-Fire Response
Avoid inhalation and skin contact. (Non-Specific -- Poisonous Liquid, n.o.s.) Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors.

Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal.

Large spills: dike far ahead of spill for later disposal. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Warning: Ethyl bis(2-chloroethyl)amine is a strong irritant. Direct contact may result in severe dermal or corneal burns. Effects may be delayed.

Signs and Symptoms of Ethyl bis(2-chloroethyl)amine Exposure: Signs and symptoms of acute exposure to ethyl bis(2-chloroethyl)amine may include strong irritation or burning of the eyes, skin, and respiratory tract. Blisters, local phlebitis (irritation of a vein) and erythema (redness of the skin) may be noted. It may cause nausea, vomiting, and severe esophageal or gastrointestinal tract irritation if ingested. Bronchopneumonia, suppression of bone marrow activity, and hearing loss are possible longer term symptoms.

Emergency Life-Support Procedures: Acute exposure to ethyl bis(2-chloroethyl)amine may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to ethyl bis(2-chloroethyl)amine.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
4. Rush to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to ethyl bis(2-chloroethyl)amine.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. Speed in removing material from the eyes is of extreme importance.
5. Wash exposed skin areas thoroughly with soap and water. Speed in removing material from skin is of extreme importance.
6. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
7. Rush to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support to all victims.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert.
5. Rush to a health care facility. (EPA, 1998)

Physical Properties

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds. The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C6H13Cl2N
Flash Point: High enough not to interfere with military use of the agent (EPA, 1998)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: -29 ° F (EPA, 1998)
Vapor Pressure: 0.24 mm Hg at 77 ° F (EPA, 1998)
Vapor Density (Relative to Air): 5.9 (EPA, 1998)
Specific Gravity: 1.0861 at 73.4 ° F (EPA, 1998)
Boiling Point: 185 ° F at 12 mm Hg (EPA, 1998)
Molecular Weight: 170.1 (EPA, 1998)
Water Solubility: data unavailable
Ionization Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

Interim AEGLs for Nitrogen Mustard-1 (538-07-8)
Exposure Period AEGL-1 AEGL-2 AEGL-3
10 minutes NR 0.13 mg/m3 2.2 mg/m3
30 minutes NR 0.044 mg/m3 0.74 mg/m3
60 minutes NR 0.022 mg/m3 0.37 mg/m3
4 hours NR 0.0056 mg/m3 0.093 mg/m3
8 hours NR 0.0028 mg/m3 0.047 mg/m3
NR = Not recommended due to insufficient data
(NAC/NRC, 2016)

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Nitrogen mustard-1; (Ethylbis(2-chloroethyl)amine; Bis(2-chloroethyl)ethylamine) (538-07-8) 0.002 mg/m3 0.022 mg/m3 0.37 mg/m3
(DOE, 2016)

Regulatory Information

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists and the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Ethylbis(2-chloroethyl)amine 538-07-8 500 pounds 500 pounds

(EPA List of Lists, 2015)

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

RELEASE THEFT SABOTAGE
Chemical of Interest CAS Number Min Conc STQ Security
Issue
Min Conc STQ Security
Issue
Min Conc STQ Security
Issue
HN1 (nitrogen mustard-1); [Bis(2-chloroethyl)ethylamine] 538-07-8 CUM 100 grams CW/CWP

(DHS, 2007)

Alternate Chemical Names

This section provides a listing of alternate names for this chemical, including trade names and synonyms.