PHYSICAL DESCRIPTION: Colorless viscous oily liquid with a weak unpleasant odor. (NTP, 1992)

none

This chemical may be sensitive to prolonged exposure to air. (NTP, 1992). Slightly water soluble.

This chemical is probably combustible. (NTP, 1992)

SYMPTOMS: Symptoms of exposure to this type of compound include cholinesterase inhibition, miosis, frontal headache, increased bronchial secretion, nausea, vomiting, sweating, abdominal cramps, diarrhea, lacrimation, increased salivation, bradycardia, cyanosis and muscular twitching of the eyelids, tongue, face and neck, possibly progressing to convulsions. Other symptoms include hyperemia of the conjunctiva, dimness of vision, rhinorrhea, bronchoconstriction, cough, fasciculation, anorexia, incontinence, eye changes, weakness, dyspnea, bronchospasm, hypotension or hypertension due to asphyxia, restlessness, anxiety, dizziness, drowsiness, tremor, ataxia, depression, confusion, neuropathy (rare), coma and death from depression of respiratory or cardiovascular systems. Exposure to this type of compound may result in giddiness, nervousness, blurred vision, discomfort (tightness) in chest, papilledema, muscular weakness, loss of reflexes, loss of sphincter control, cardiac arrhythmias, various degrees of heart block and cardiac arrest. It may also result in spasm of accommodation, aching pain in and about the eye, nystagmus, delayed distal axonopathy and parethesias and paralysis of limbs. A decrease in blood pressure may occur. Respiratory failure may also occur.

ACUTE/CHRONIC HAZARDS: This compound is toxic by ingestion. It is a CHOLINESTERASE INHIBITOR. When heated to decomposition it emits toxic fumes of sulfur oxides and phosphorus oxides. (NTP, 1992)

A thioorganophosphate, ester. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

• Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

No information available.

Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should keep this material in a tightly closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)

MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

RECOMMENDED RESPIRATOR: When working with this chemical, wear a NIOSH-approved full face chemical cartridge respirator equipped with the appropriate organic vapor cartridges. If that is not available, a half face respirator similarly equipped plus airtight goggles can be substituted. However, please note that half face respirators provide a substantially lower level of protection than do full face respirators. (NTP, 1992)

No information available.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, administer a slurry of activated charcoal in water and simultaneously call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

• BUTANEDIOIC ACID, ((DIMETHOXYPHOSPHINYL)THIO)-, DIETHYL ESETER
• CARBETHOXY MALAOXON
• DIETHYL MERCAPTOSUCCINATE S-ESTER WITH O,O-DIMETHYL PHOSPHOROTHIOATE
• DIETHYL [(DIMETHOXYPHOSPHINO)THIO]BUTANEDIOATE
• DIETHYL((DIMETHOXYPHOSPHINYL)THIO)BUTANEDIOATE
• ((DIMETHOXYPHOSPHINYL)THIO)BUTANEDIOIC ACID DIETHYL ESTER
• DL-MALAOXON
• LIROMAT
• MALAOXON
• MALAOXONE
• MALATHION OXON
• MALATHION-O-ANALOG
• MALOXON
• MERCAPTOSUCCINIC ACID DIETHYL ESTER, S-ESTER WITH O,O-DIMETHYLPHOSPHOROTHIOATE
• NCI-C08628
• O,O-DIMETHYL S-1,2-BIS(ETHOXYCARBONYL)ETHYL PHOSPHOROTHIOATE
• O,O-DIMETHYL-S-(1,2-DICARBETHOXY)ETHYL PHOSPHOROTHIOATE
• O,O-DIMETHYL-S-1,2-BIS(ETHOXYCARBONYL)ETHYL PHOSPHOROTHIOATE
• OXYCARBOPHOS
• PHOSPHOROTHIOIC ACID, O,O-DIMETHYL ESTER, S-ESTER WITH 1,2-BIS(METHOXY-CARBONYL)ETHANETHIOL
• S-(1,2-DIETHOXYCARBONYL)ETHYL O,O-DIMETHYL PHOSPHOROTHIOATE
• SUCCINIC ACID, MERCAPTO-, DIETHYL ESTER, DIMETHYL PHOSPHATE
• SUCCINIC ACID, MERCAPTO-, DIETHYL ESTER, S-ESTER WITH O,O-DIMETHYL PHOSPHOROTHIOATE
• SUCCINIC ACID, MERCAPTO-, DIETHYL ESTER, S-ESTER WITH O,O-DIMETHYLPHOSPHORO-
• THIOATE