Chemical Datasheet
RESERPINE |
Chemical Identifiers
The
Chemical Identifier fields
include common identification numbers, the
NFPA diamond
U.S. Department of Transportation hazard labels, and a general
description of the chemical. The information in CAMEO Chemicals comes
from a variety of
data sources.
CAS Number | UN/NA Number | DOT Hazard Label | USCG CHRIS Code |
---|---|---|---|
|
|
none | |
NIOSH Pocket Guide | International Chem Safety Card | ||
none | none |
NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: White or cream to slightly yellow crystals or crystalline powder. Odorless with a bitter taste. (NTP, 1992)
Hazards
The
Hazard fields
include
special hazard alerts
air and water
reactions, fire hazards, health hazards, a reactivity profile, and
details about
reactive groups assignments
and
potentially incompatible absorbents.
The information in CAMEO Chemicals comes from a variety of
data sources.
Reactivity Alerts
none
Air & Water Reactions
Insoluble in water. Reacts slowly with air and water. Darkens slowly on exposure to light.
Fire Hazard
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound may include lowered blood pressure, sedation, bradycardia, drowsiness, nasal congestion, weight gain and severe mental depression which may lead to suicide. Other symptoms include lethargy, vertigo, gastrointestinal upset, dyspnea, flushing and parkinsonism. It can cause nightmares and an increase in gastrointestinal tone and motility with abdominal cramps and diarrhea. It can also cause insomnia, cardiotoxic effects (such as premature ventricular contractions and other arrhythmias, possible sensitization to digitalis, fluid retention and congestive failure), fatigue, weakness, excitement, irrational behavior and sodium retention edema. Exposure can cause dryness of the mouth, pruritus and skin rashes, angina-like syndrome, blurred vision, breast engorgement and galactorrhea, impotence, epistaxis, difficulty in micturition, purpura, bronchospasm, thrombocytopenia, effects on the endocrine system, interference with color vision, hematemesis, systemic lupus erythematosus and breast cancer. Exposure can also cause an increase in appetite, anxiety, headache and disturbance of ejaculation. Other symptoms include nausea with anorexia, excessive salivation, reduction in emotional tension, sleepiness, dizziness, apathy, confusion, restlessness, hallucinations, vomiting, excessive secretory and motor activity of the stomach (which may eventually lead to the formation of peptic ulcer with pain, hemorrhage and perforation), blockade of peripheral adrenergic nerves (which may cause peripheral vasodilatation), motor disturbances (apparently of the extrapyramidal system characterized by stiffness with aching pain in the legs, tremors and various types of dystonia and catatonia), hypothermia, cardiovascular collapse and coma with blushing. Chronic exposure may cause hormonal disturbances, notably mild feminization of adult males with gynecomastia and lactation. Anginal pain and extrasystoles have occurred. Psychotropic effects have also occurred. Eyes may appear slightly flushed due to the dilation of conjunctival blood vessels. Lacrimation, slight miosis and ocular spasms may occur. Eye effects also include conjunctival hyperemia. This chemical may cause serious respiratory problems in infants born to mothers exposed to it during pregnancy. Intramuscular or intravenous injection may cause postural hypotension and duodenal ulcers.
ACUTE/CHRONIC HAZARDS: This compound is highly toxic by ingestion. It is harmful if inhaled or absorbed through the skin. It may cause irritation. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides. (NTP, 1992)
ACUTE/CHRONIC HAZARDS: This compound is highly toxic by ingestion. It is harmful if inhaled or absorbed through the skin. It may cause irritation. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides. (NTP, 1992)
Reactivity Profile
RESERPINE is a weak base and can form salts with strong acids. Incompatible with oxidizing agents and reducing agents.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents
No information available.
Response Recommendations
The
Response Recommendation fields
include isolation and evacuation distances, as well as recommendations for
firefighting, non-fire response, protective clothing, and first aid. The
information in CAMEO Chemicals comes from a variety of
data sources.
Isolation and Evacuation
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.
FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.
FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
Firefighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)
STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)
Protective Clothing
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)
SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)
Physical Properties
The
Physical Property fields
include properties such as vapor pressure and
boiling point, as well as explosive limits and
toxic exposure thresholds
The information in CAMEO Chemicals comes from a variety of
data sources.
Note: For Vapor Density and Specific Gravity, comparing the value to 1.0 can tell you if the chemical will likely sink/rise in air or sink/float in fresh water (respectively). Short phrases have been added to those values below as an aid. However, make sure to also consider the circumstances of a release. The Vapor Density comparisons are only valid when the gas escaping is at the same temperature as the surrounding air itself. If the chemical is escaping from a container where it was pressurized or refrigerated, it may first escape and behave as a heavy gas and sink in the air (even if it has a Vapor Density value less than 1). Also, the Specific Gravity comparisons are for fresh water (density 1.0 g/mL). If your spill is in salt water (density about 1.027 g/mL), you need to adjust the point of comparison. There are some chemicals that will sink in fresh water and float in salt water.
Note: For Vapor Density and Specific Gravity, comparing the value to 1.0 can tell you if the chemical will likely sink/rise in air or sink/float in fresh water (respectively). Short phrases have been added to those values below as an aid. However, make sure to also consider the circumstances of a release. The Vapor Density comparisons are only valid when the gas escaping is at the same temperature as the surrounding air itself. If the chemical is escaping from a container where it was pressurized or refrigerated, it may first escape and behave as a heavy gas and sink in the air (even if it has a Vapor Density value less than 1). Also, the Specific Gravity comparisons are for fresh water (density 1.0 g/mL). If your spill is in salt water (density about 1.027 g/mL), you need to adjust the point of comparison. There are some chemicals that will sink in fresh water and float in salt water.
Chemical Formula: |
|
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point:
507 to 509°F
(decomposes)
(NTP, 1992)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: data unavailable
Boiling Point: data unavailable
Molecular Weight:
608.7
(NTP, 1992)
Water Solubility:
less than 1 mg/mL
at 72°F
(NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable
AEGLs (Acute Exposure Guideline Levels)
No AEGL information available.ERPGs (Emergency Response Planning Guidelines)
No ERPG information available.PACs (Protective Action Criteria)
No PAC information available.Regulatory Information
The
Regulatory Information fields
include information from
the U.S. Environmental Protection Agency's Title III Consolidated List of
Lists,
the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility
Anti-Terrorism Standards,
and the U.S. Occupational Safety and Health Administration's
Process Safety Management of Highly Hazardous Chemicals Standard List
(see more about these
data sources).
EPA Consolidated List of Lists
Regulatory Name | CAS Number/ 313 Category Code |
EPCRA 302 EHS TPQ |
EPCRA 304 EHS RQ |
CERCLA RQ | EPCRA 313 TRI |
RCRA Code |
CAA 112(r) RMP TQ |
---|---|---|---|---|---|---|---|
Reserpine | 50-55-5 | 5000 pounds | U200 |
(EPA List of Lists, 2024)
CISA Chemical Facility Anti-Terrorism Standards (CFATS)
No regulatory information available.OSHA Process Safety Management (PSM) Standard List
No regulatory information available.Alternate Chemical Names
This section provides a listing of alternate names for this chemical,
including trade names and synonyms.
- ABESTA
- ABICOL
- ADELFAN
- ADELPHANE
- ADELPHIN
- ALKARAU
- ALKASERP
- ALSERIN
- ANQUIL
- APOPLON
- APSICAL
- ASCOSERP
- AUSTRAPINE
- BANASIL
- BANISIL
- BENAZYL
- BENDIGON
- BENZ[G]INDOLO[2,3-A]QUINOLIZINE, YOHIMBAN-16-CARBOXYLIC ACID DERIV.
- 3-BETA,20-ALPHA-YOHIMBAN-16-BETA-CARBOXYLIC ACID, 18-BETA-HYDROXY-11,17-ALPHA-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE (ESTER)
- 3BETA,20ALPHA-YOHIMBAN-16BETA-CARBOXYLIC ACID, 18BETA-HYDROXY-11,17ALPHA-DIMETHOXY- METHYL ESTER 3,4,5-TRIMETHOXYBENZOATE (ESTER)
- 3BETA,20ALPHA-YOHIMBAN-16BETA-CARBOXYLIC ACID, 18BETA-HYDROXY-11,17ALPHA-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE
- BIOSERPINE
- BRINDERDIN
- BRISERINE
- BUTISERPAZIDE-25
- CARDIOSERPIN
- CARDITIVO
- CARPACIL
- CARRSERP
- CRYSTOSERPINE
- DAREBON
- DESERPINE
- DIUPRES
- EBERPINE
- EBSERPINE
- ELFANEX
- ELSERPINE
- ENIPRESSER
- ENT 50146
- ESCASPERE
- ESERPINE
- ESKASERP
- GAMMASERPINE
- GILUCARD
- H 520
- HELFOSERPIN
- HEXAPLIN
- HIPOSERPIL
- HISERPIA
- HYDROMOX R
- HYDROPRES
- HYPERCAL B
- HYPERTANE FORTE
- HYPERTENSAN
- IDOSERP
- INTERPINA
- KITINE
- KLIMANOSID
- LEMISERP
- LOWESERP
- MARNITENSION SIMPLE
- MAVISERPIN
- MAYSERPINE
- MEPHASERPIN
- METATENSIN
- METHYL 11,17ALPHA-DIMETHOXY-18BETA-(3,4,5-TRIMETHOXYBENZOYLOXY)-3BETA,20ALPHA-YOHIMBANE-16BETA-CARBOXYLATE
- METHYL O-(3,4,5-TRIMETHOXYBENZOYL)RESERPATE
- METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOATE (ESTER)
- METHYLRESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID
- METHYLRESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER
- MODENOL
- NAQUIVAL
- NCI-C50157
- NEMBUSERPIN
- NEO-SERP
- NEOSERFIN
- NEOSLOWTEN
- ORTHOSERPINA
- PERSKLERAN
- PRESSIMEDIN
- PURSERPINE
- QUIESCIN
- R-E-S
- RAU-SED
- RAUCAP
- RAUDIXIN
- RAUGAL
- RAULEN
- RAULOYDIN
- RAUMORINE
- RAUNERVIL
- RAUNORINE
- RAUPASIL
- RAUPOID
- RAURINE
- RAUSAN
- RAUSEDIL
- RAUSEDYL
- RAUSERPIN
- RAUSERPINE
- RAUSERPOL
- RAUSINGLE
- RAUTRIN
- RAUWASEDIN
- RAUWILID
- RAUWILOID
- RAUWIPUR
- RAUWOLEAF
- RECIPIN
- RESALTEX
- RESEDREX
- RESEDRIL
- RESERBAL
- RESERCAPS
- RESERCEN
- RESERFIA
- RESERLOR
- RESERP
- RESERPAMED
- RESERPENE
- RESERPEX
- RESERPIC ACID METHYL ESTER 3,4,5-TRIMETHOXYBENZOATE (ESTER)
- RESERPIL
- RESERPIN
- RESERPINA
- RESERPINE
- (-)-RESERPINE
- RESERPOID
- RESERPUR
- RESERUTIN
- RESIDINE
- RESINE
- RESOCALM
- RESPERIN
- RESPITAL
- RESTRAN
- REZERPIN
- RISERPA
- RIVASIN
- ROXEL
- ROXINOID
- SALUPRES
- SANDRIL
- SANDRON
- SEDARAUPIN
- SEDARAUPINA
- SEDSERP
- SEOMINAL
- SERFIN
- SERFOLIA
- SEROLFIA
- SERP-AFD
- SERPALAN
- SERPALOID
- SERPANRAY
- SERPASIL
- SERPASIL PREMIX
- SERPASOL
- SERPATE
- SERPAZOL
- SERPEN
- SERPENA
- SERPENTIL
- SERPENTINA
- SERPICON
- SERPILOID
- SERPILUM
- SERPINE
- SERPINE (PHARMACEUTICAL)
- SERPIPUR
- SERPIVITE
- SERPOGEN
- SERPOID
- SERPONE
- SERTABS
- SERTENS
- SERTINA
- SK-RESERPINE
- SOLFO SERPINE
- SUPERGAN
- T-SERP
- TEMPO-RESERPINA
- TEMPOSERPINE
- TENSANYL
- TENSIONAL
- TENSIONORME
- TERBOLAN
- TRANSERPIN
- 3,4,5-TRIMETHOXYBENZOYL METHYL RESERPATE
- TRISERPIN
- TYLANDRIL
- UNILORD
- UNITENSEN
- USAF CB-27
- V-SERP
- VERILOID
- VIO-SERPINE
- VIXO
- YOHIMBAN-16-CARBOXYLIC ACID DERIVATIVE OF BENZ(G)INDOLO(2,3-A)QUINOLIZINE