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Chemical Datasheet

ENDOTHION

6.1 - Poisonous materials
Chemical Identifiers | Hazards | Response Recommendations | Physical Properties | Regulatory Information | Alternate Chemical Names

Chemical Identifiers

CAS Number - Chemical Abstracts Service registry number. Unique identification number assigned to this chemical by the American Chemical Society.

UN/NA Number - The United Nations-North America number (also called UN number or DOT number). 4-digit number identifying an individual chemical or group of chemicals with similar characteristics. Required on shipping papers; often shown on placards or labels. This numbering system was developed by the U.S. Department of Transportation, and then became the UN standard system for classifying hazardous materials.

DOT Hazard Label - U.S. Department of Transportation hazard warning label for the chemical (such as flammable liquid or corrosive). This label must be displayed on shipped packages, railroad tank cars, and tank trucks according to specifications described in 49 CFR 172.

CHRIS Code - 3-letter code used by the U.S. Coast Guard to identify individual chemicals included in its CHRIS (Chemical Hazards Response Information System) manual.

NFPA 704 - Text description of the diamond-shaped placard, which contains codes indicating the level of the chemical's health, flammability, and instability hazards, along with special hazards such as water- and air-reactivity. See a guide to the NFPA diamond.

General Description - Brief description of the chemical's general appearance, behavior, and hazardousness.

List of data sources.
CAS Number UN/NA Number DOT Hazard Label CHRIS Code
  • 2778-04-3
  • Poison
none
NFPA 704
data unavailable
General Description
White crystals with a slight odor. Used as an insecticide. Not sold in the USA or Canada. (EPA, 1998)

Hazards

Reactivity Alerts - Special alerts if the chemical is especially reactive (see list of reactivity alerts).

Air & Water Reactions - Special alerts if the chemical reacts with air, water, or moisture.

Fire Hazard - Description of the chemical's fire hazards (such as flammability, explosion risk, or byproducts that may evolve if the chemical is burned).

Health Hazard - Description of the chemical's health hazards (such as toxicity, flammability, or corrosivity).

Reactivity Profile - Description of the chemical's potential reactivity with other chemicals, air, and water. Also includes any other intrinsic reactive hazards (such as polymerizable or peroxidizable).

Reactive Groups - List of reactive groups that the chemical is assigned to, based on its known chemistry. Reactive groups are categories of chemicals that react in similar ways because their chemical structures are similar. Reactive groups are used to predict reactivity when you add a chemical to MyChemicals. Read more about reactive groups.

Potentially Incompatible Absorbents - Absorbents are products that can be used to soak up liquids from spills. However, some absorbents can react with particular chemicals (that is, they are incompatible), so caution should be used in selecting the correct absorbent for your situation. This section provides a list of potentially incompatible absorbents that have been known to react with liquids assigned to one or more of the reactive groups listed on this datasheet. Read more about absorbents, including situations to watch out for.

List of data sources.
Reactivity Alerts
none
Air & Water Reactions
No rapid reaction with air. No rapid reaction with water.
Fire Hazard
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Cylinder may explode in heat or fire. Fire and runoff from fire control water may produce irritating or poisonous gases. When heated to decomposition, it emits very toxic fumes of phosphorous oxides and sulfur oxides. (EPA, 1998)
Health Hazard
This material is poisonous to humans. Its toxic effects are most likely related to action on the nervous system. (EPA, 1998)
Reactivity Profile
Organothiophosphates, such as ENDOTHION, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

Response Recommendations

Isolation and Evacuation - Isolation and evacuation distance recommendations from the Emergency Response Guidebook (ERG).

Firefighting - Response recommendations if the chemical is on fire (or near a fire).

Non-Fire Response - Response recommendations if the chemical isn't on fire (or near a fire).

Protective Clothing - Recommendations for protective gear.

Dupont Tychem® Suit Fabrics - A table of normalized breakthrough times for DuPont Tychem suit fabrics for the chemical, if available.

First Aid - Recommended first aid treatment for people exposed to the chemical.

List of data sources.
Isolation and Evacuation
Excerpt from GUIDE 152 [Substances - Toxic (Combustible)]:

As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2012)
Firefighting
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers from fire area if you can do it without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Wear positive pressure breathing apparatus and special protective clothing.

(Non-Specific -- Organophosphorus Pesticide, n.o.s.) This material may burn, but does not ignite readily. For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. (EPA, 1998)
Non-Fire Response
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors.

Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal.

Small dry spills: with clean shovel place material into clean, dry containers and cover; move containers from spill area.

Large spills: dike far ahead of spill for later disposal. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Warning: Effects may be delayed up to 12 hours. Caution is advised.

Note: Endothion is a cholinesterase inhibitor.

Signs and Symptoms of Endothion Exposure: Acute exposure to endothion may produce the following signs and symptoms: sweating, pinpoint pupils, blurred vision, headache, dizziness, profound weakness, muscle spasms, seizures, and coma. Mental confusion and psychosis may occur. Excessive salivation, nausea, vomiting, anorexia, diarrhea, and abdominal pain may also occur. The heart rate may decrease following oral exposure or increase following dermal exposure. Chest pain may be noted. Hypotension (low blood pressure) may be observed, although hypertension (high blood pressure) is not uncommon. Respiratory symptoms include dyspnea (shortness of breath), pulmonary edema, respiratory depression, and respiratory paralysis.

Emergency Life-Support Procedures: Acute exposure to endothion exposure may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to endothion.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to endothion.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of endothion is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of endothion may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3- 1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

Physical Properties

This section contains physical properties, flammability limits, and toxic thresholds for this chemical (see definitions of each property). More property data is available for common chemicals.

See also the Levels of Concern guide for information on AEGLs, ERPGs, PACs, and IDLH values.

List of data sources.
Chemical Formula:
  • C9H13O6PS
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: 194 to 205 ° F (EPA, 1998)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: data unavailable
Boiling Point: data unavailable
Molecular Weight: 280.24 (EPA, 1998)
Water Solubility: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Endothion (2778-04-3) 1.5 mg/m3 17 mg/m3 17 mg/m3
(SCAPA, 2012)

Regulatory Information

This section contains regulatory information from the Title III Consolidated List of Lists (see details about each regulatory field).

List of data sources.
Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Endothion 2778-04-3 500/10000 500

(EPA List of Lists, 2012)

Alternate Chemical Names

This section provides a listing of alternate names for this chemical, including trade names and synonyms.