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Chemical Datasheet
ISOPROPANOL |
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Chemical Identifiers
CAS Number |
UN/NA Number |
DOT Hazard Label |
USCG CHRIS Code |
- 67-63-0
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NIOSH Pocket Guide |
International Chem Safety Card |
Isopropyl alcohol
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NFPA 704
General Description
Volatile, colorless liquid with a sharp musty odor like rubbing alcohol. Flash point of 53°F. Vapors are heavier than air and mildly irritating to the eyes, nose, and throat. Density approximately 6.5 lb / gal. Used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, soaps, window cleaners. Sold in 70% aqueous solution as rubbing alcohol.
Hazards
Reactivity Alerts
- Highly Flammable
- Peroxidizable Compound
Air & Water Reactions
Highly flammable. Water soluble.
Fire Hazard
Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids will float on water. (ERG, 2024)
Health Hazard
Vapors cause mild irritation of eyes and upper respiratory tract; high concentrations may be anesthetic. Liquid irritates eyes and may cause injury; harmless to skin; if ingested causes drunkenness and vomiting. (USCG, 1999)
Reactivity Profile
ISOPROPANOL reacts with air or oxygen to form dangerously unstable peroxides. Contact with 2-butanone increases the rate of peroxide formation. An explosive reaction occurs when it is heated with (aluminum isopropoxide + crotonaldehyde). Forms explosive mixtures with trinitromethane and hydrogen peroxide. Reacts with barium perchlorate to form a highly explosive compound. Ignites on contact with dioxygenyl tetrafluoroborate, chromium trioxide and potassium-tert-butoxide. Vigorous reactions occur with (hydrogen + palladium), nitroform, oleum, COCl2, aluminum triisopropoxide and oxidizing agents. Reacts explosively with phosgene in the presence of iron salts. Incompatible with acids, acid anhydrides, halogens and aluminum (NTP, 1992). Isopropanol can react with PCl3, forming toxic HCl gas. (Logsdon, John E., Richard A. Loke., "Isopropyl Alcohol." Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc. 1996.).
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents
Use caution: Liquids with this reactive group classification have been
known to react with the
absorbent
listed below.
- Cellulose-Based Absorbents
Response Recommendations
Isolation and Evacuation
Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.
LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).
FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
Firefighting
Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.
SMALL FIRE: Dry chemical, CO2, water spray or alcohol-resistant foam. Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).
LARGE FIRE: Water spray, fog or alcohol-resistant foam. Avoid aiming straight or solid streams directly onto the product. If it can be done safely, move undamaged containers away from the area around the fire.
FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)
Non-Fire Response
Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.
LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)
Protective Clothing
Excerpt from NIOSH Pocket Guide for Isopropyl alcohol:
Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.
Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.
Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.
Remove: WHEN WET (FLAMMABLE) - Work clothing that becomes wet should be immediately removed due to its flammability hazard (i.e., for liquids with a flash point <100°F).
Change: No recommendation is made specifying the need for the worker to change clothing after the workshift. (NIOSH, 2024)
DuPont Tychem® Suit Fabrics
Normalized Breakthrough Times (in Minutes)
Chemical |
CAS Number |
State |
QS |
QC |
SL |
C3 |
TF |
TP |
RC |
TK |
RF |
Isopropanol |
67-63-0 |
Liquid |
|
imm |
>480 |
>480 |
>480 |
>480 |
>480 |
>480 |
>480 |
Isopropanol (70%) |
67-63-0 |
Liquid |
|
imm |
>480 |
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>480 |
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Isopropyl alcohol |
67-63-0 |
Liquid |
|
imm |
>480 |
>480 |
>480 |
>480 |
>480 |
>480 |
>480 |
Isopropyl alcohol (70%) |
67-63-0 |
Liquid |
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imm |
>480 |
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>480 |
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Propan -2-ol |
67-63-0 |
Liquid |
|
imm |
>480 |
>480 |
>480 |
>480 |
>480 |
>480 |
>480 |
Propan -2-ol (70%) |
67-63-0 |
Liquid |
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imm |
>480 |
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>480 |
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Special Warning from DuPont: Tychem® and Tyvek® fabrics should not be
used around heat, flames, sparks or in potentially flammable or
explosive environments. Only...
(DuPont, 2024)
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
INGESTION: DO NOT INDUCE VOMITING. Volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Physical Properties
Flash Point:
53°F
(NTP, 1992)
Lower Explosive Limit (LEL):
2 %
(NTP, 1992)
Upper Explosive Limit (UEL):
12 %
(NTP, 1992)
Autoignition Temperature:
750°F
(USCG, 1999)
Melting Point:
-127.3°F
(NTP, 1992)
Vapor Pressure:
33 mmHg
at 68°F
; 40 mmHg at 74.8°F
(NTP, 1992)
Vapor Density (Relative to Air):
2.07
(NTP, 1992)
- Heavier than air; will sink
Specific Gravity:
0.785
at 68°F
(USCG, 1999)
- Less dense than water; will float
Boiling Point:
180.5°F
at 760 mmHg
(NTP, 1992)
Molecular Weight:
60.1
(NTP, 1992)
Water Solubility:
greater than or equal to 100 mg/mL
at 72°F
(NTP, 1992)
Ionization Energy/Potential:
10.10 eV
(NIOSH, 2024)
IDLH:
2000 ppm
; Based on 10% of the lower explosive limit.
(NIOSH, 2024)
AEGLs (Acute Exposure Guideline Levels)
No AEGL information available.
ERPGs (Emergency Response Planning Guidelines)
No ERPG information available.
PACs (Protective Action Criteria)
Chemical |
PAC-1 |
PAC-2 |
PAC-3 |
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Isopropyl alcohol (67-63-0)
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400 ppm |
2000 ppm |
12000 ppm |
LEL = 20000 ppm |
(DOE, 2024)
Regulatory Information
EPA Consolidated List of Lists
Regulatory Name |
CAS Number/ 313 Category Code |
EPCRA 302 EHS TPQ |
EPCRA 304 EHS RQ |
CERCLA RQ |
EPCRA 313 TRI |
RCRA Code |
CAA 112(r) RMP TQ |
Isopropyl alcohol (mfg-strong acid process) |
67-63-0 |
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313 |
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(EPA List of Lists, 2024)
CISA Chemical Facility Anti-Terrorism Standards (CFATS)
No regulatory information available.
OSHA Process Safety Management (PSM) Standard List
No regulatory information available.
Alternate Chemical Names
- ALCOJEL
- ALCOSOLVE
- ALCOSOLVE 2
- AUTOSEPT
- AVANTIN
- AVANTINE
- CHROMAR
- COMBI-SCHUTZ
- DIMETHYL CARBINOL
- DIMETHYLCARBINOL
- HARTOSOL
- 2-HYDROXYPROPANE
- IMSOL A
- IPA
- IPS 1
- IPS 1 (ALCOHOL)
- ISO-PROPANOL
- ISO-PROPYL ALCOHOL
- ISOHOL
- ISOPROPANOL
- ISOPROPYL ALCOHOL
- ISOPROPYL ALCOHOL (MFG-STRONG ACID PROCESS)
- LUTOSOL
- 1-METHYLETHANOL
- 1-METHYLETHYL ALCOHOL
- N-PROPAN-2-OL
- PETROHOL
- PRO
- PROPAN-2-OL
- 2-PROPANOL
- PROPOL
- 2-PROPYL ALCOHOL
- RUBBING ALCOHOL
- SEC-PROPANOL
- SEC-PROPYL ALCOHOL
- SPECTRAR
- STERISOL HAND DISINFECTANT
- TAKINEOCOL