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Chemical Datasheet

TRICRESYL PHOSPHATE

 6.1 - Poison

Chemical Identifiers

CAS Number UN/NA Number DOT Hazard Label USCG CHRIS Code
  • 78-30-8   (tri-ortho-cresyl phosphate)
  • 1330-78-5   (tri-para-cresyl phosphate)
  • 2574
  • Poison
  • TCP
NIOSH Pocket Guide International Chem Safety Card
Triorthocresyl phosphate
  • TRI-o-CRESYL PHOSPHATE
NFPA 704
Diamond Hazard Value Description
1
1 0
Blue Health 1 Can cause significant irritation.
Red Flammability 1 Must be preheated before ignition can occur.
Yellow Instability 0 Normally stable, even under fire conditions.
White Special
(NFPA, 2010)
General Description
A colorless,odorless liquid. Insoluble in water and slightly denser than water. Toxic by ingestion and skin absorption. Used to make plastics and lubricants.

Hazards

Reactivity Alerts
none
Air & Water Reactions
Insoluble in water.
Fire Hazard
Excerpt from 151 Polymerizable warning [Substances - Toxic (Non-Combustible)]:

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways. (ERG, 2020)
Health Hazard
Vapors may irritate eyes, but only at high temperatures. Ingestion of liquid may cause severe damage to central nervous system and death if significant amounts of the toxic ortho-isomer are present. (USCG, 1999)
Reactivity Profile
Organophosphates, such as TRICRESYL PHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

Response Recommendations

Isolation and Evacuation
Excerpt from 151 Polymerizable warning [Substances - Toxic (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)
Firefighting
Excerpt from 151 Polymerizable warning [Substances - Toxic (Non-Combustible)]:

SMALL FIRE: Dry chemical, CO2 or water spray.

LARGE FIRE: Water spray, fog or regular foam. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal. Avoid aiming straight or solid streams directly onto the product.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2020)
Non-Fire Response
Excerpt from 151 Polymerizable warning [Substances - Toxic (Non-Combustible)]:

Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2020)
Protective Clothing
Excerpt from NIOSH Pocket Guide for Triorthocresyl phosphate:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: No recommendation is made specifying the need for eye protection.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: No recommendation is made specifying the need for the worker to change clothing after the workshift. (NIOSH, 2023)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, administer a slurry of activated charcoal in water and simultaneously call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Physical Properties

Chemical Formula:
  • C21H21O4P
Flash Point: 437°F (NTP, 1992)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: 725°F (NTP, 1992)
Melting Point: -22 to -13°F (NTP, 1992)
Vapor Pressure: 1.7e-06 mmHg at 77°F (NTP, 1992)
Vapor Density (Relative to Air): 12.7 (NTP, 1992) - Heavier than air; will sink
Specific Gravity: 1.16 at 68°F (USCG, 1999) - Denser than water; will sink
Boiling Point: 770°F at 760 mmHg (Slight decomposition) (NTP, 1992)
Molecular Weight: 368.37 (NTP, 1992)
Water Solubility: less than 1 mg/mL at 68°F (NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: 40 mg/m3 [From NPG: Triorthocresyl phosphate] (NIOSH, 2023)

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Tri-o-tolyl phosphate; (Triorthocresyl phosphate) (78-30-8) 0.3 ppm 13 ppm 40 ppm
(DOE, 2018)

Regulatory Information

EPA Consolidated List of Lists

No regulatory information available.

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

Alternate Chemical Names