SEMICARBAZIDE HYDROCHLORIDE

Snow white crystals. Used as a reagent for ketones and aldehydes with which it affords crystalline compounds having characteristic melting points. (EPA, 1998)

none

Water soluble. Acid reaction in water. (NTP, 1992)

When heated to decomposition, it emits very toxic fumes of nitrogen oxides and hydrogen chloride. (EPA, 1998)

Toxic by ingestion. (EPA, 1998)

When heated to decomposition, it emits very toxic fumes of nitrogen oxides and hydrogen chloride. [EPA, 1998].

• Amides and Imides
• Azo, Diazo, Azido, Hydrazine, and Azide Compounds
• Salts, Acidic

No information available.

Excerpt from 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

(Non-Specific -- Poisonous Solid, n.o.s.) Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.

(Non-Specific -- Poisonous Solid, n.o.s.) This material may burn, but does not ignite readily. For small fires use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. (EPA, 1998)

(Non-Specific -- Poisonous Solid, n.o.s.) Isolate hazard area. Stay upwind; keep out of low areas. Do not touch spilled material. Absorb small spills with sand or other noncombustible absorbent material and place into containers for later disposal. Take up small, dry spills with clean shovel; place material into clean, dry container and cover; move containers from spill area. Dike far ahead of large spills for later disposal. (EPA, 1998)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

No information available.

Signs and Symptoms of Semicarbazide Hydrochloride Exposure: No information on specific clinical effects of exposure to semicarbazide hydrochloride was found in available references. However, animal data indicate that signs and symptoms of acute exposure to semicarbazide hydrochloride may include loss of coordination, dizziness, tremors, convulsions, and seizures.

Emergency Life-Support Procedures: Acute exposure to semicarbazide hydrochloride may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to semicarbazide hydrochloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to semicarbazide hydrochloride.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g in children (1/2 to 1 oz) (1 to 2 g/kg in infants), and 30 to 100 g (1 to 3-1/2 oz) in adults. Administer one dose of a cathartic, mixed with charcoal or given separately.
5. Transport to a health care facility. (EPA, 1998)

• AMIDOUREA HYDROCHLORIDE
• AMINOUREA HYDROCHLORIDE
• CARBAMYL HYDRAZINE HYDROCHLORIDE
• CARBAMYLHYDRAZINE HYDROCHLORIDE
• HYDRAZINECARBOXAMIDE MONOHYDROCHLORIDE
• HYDRAZINECARBOXAMIDE, HYDROCHLORIDE
• HYDRAZINECARBOXAMIDE, MONOHYDROCHLORIDE
• SEMICARBAZIDE CHLORIDE
• SEMICARBAZIDE HYDROCHLORIDE
• SEMICARBAZIDE, HYDROCHLORIDE
• SEMICARBAZIDE, MONOHYDROCHLORIDE