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Chemical Datasheet
PHOSPHAMIDON |
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Chemical Identifiers
CAS Number |
UN/NA Number |
DOT Hazard Label |
USCG CHRIS Code |
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none
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NIOSH Pocket Guide |
International Chem Safety Card |
none
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NFPA 704
data unavailable
General Description
Pale yellow oily liquid with a faint odor. Used as an insecticide for citrus, cotton, and deciduous fruit and nuts. and as an acaricide. (EPA, 1998)
Hazards
Reactivity Alerts
none
Air & Water Reactions
Water soluble. Hydrolyzed by alkali with a half-life at 73°F of 13.8 days at pH 7 and 2.2 days at pH 10 (NTP, 1992).
Fire Hazard
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Heat above 320F may cause decomposition and evolution of highly toxic fumes of phosphorus oxides and chlorides. Hydrolyzes in alkali. Stable in neutral and acid media. Hydrolyzes in alkali. (EPA, 1998)
Health Hazard
This material is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150-lb person. It is a cholinesterase inhibitor. (EPA, 1998)
Reactivity Profile
PHOSPHAMIDON is corrosive to iron, tin and aluminum. Incompatible with alkaline preparations and should not be mixed with copper oxychloride, captan, folpet or sulfur. (NTP, 1992)
Belongs to the Following Reactive Group(s)
- Amides and Imides
- Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
- Halogenated Organic Compounds
- Hydrocarbons, Aliphatic Unsaturated
Potentially Incompatible Absorbents
Use caution: Liquids with this reactive group classification have been
known to react with the
absorbent
listed below.
Response Recommendations
Isolation and Evacuation
Excerpt from 152
[Substances - Toxic (Combustible)]:
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.
FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)
Firefighting
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move containers from fire area if you can do it without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) This material may burn, but does not ignite readily. For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. (EPA, 1998)
Non-Fire Response
Caution : Explosion potential is high. Containers may explode in heat of fire. Highly toxic phosphorus oxides and chlorides may be emitted when phosphamidon is heated to decomposition. Avoid sources of extreme heat.
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors.
Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal.
Large spills: dike far ahead of spill for later disposal. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Note: Phosphamidon is a cholinesterase inhibitor.
Signs and Symptoms of Acute Phosphamidon Exposure: Acute exposure to phosphamidon may produce pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may also occur. The heart rate may decrease following oral exposure or increase following dermal exposure. Hypotension (low blood pressure) may occur, although hypertension (high blood pressure) is not uncommon. Chest pain may be noted. Respiratory effects include dyspnea (shortness of breath), respiratory depression, and respiratory paralysis. Psychosis may occur.
Emergency Life-Support Procedures: Acute exposure to phosphamidon may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to phosphamidon.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self- exposure to phosphamidon.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of phosphamidon is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4.Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of phosphamidon may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)
Physical Properties
Flash Point:
greater than 200°F
(NTP, 1992)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point:
-49°F
(EPA, 1998)
Vapor Pressure:
2.5e-05 mmHg
at 68°F
(EPA, 1998)
Vapor Density (Relative to Air): data unavailable
Specific Gravity:
1.2132
at 77°F
(EPA, 1998)
- Denser than water; will sink
Boiling Point:
324°F
at 1.5 mmHg
(EPA, 1998)
Molecular Weight:
299.7
(EPA, 1998)
Water Solubility:
greater than or equal to 100 mg/mL
at 72°F
(NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable
AEGLs (Acute Exposure Guideline Levels)
No AEGL information available.
ERPGs (Emergency Response Planning Guidelines)
No ERPG information available.
PACs (Protective Action Criteria)
Chemical |
PAC-1 |
PAC-2 |
PAC-3 |
Phosphamidon; (Famfos) (13171-21-6)
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0.027 mg/m3 |
0.3 mg/m3 |
21 mg/m3 |
(DOE, 2018)
Regulatory Information
EPA Consolidated List of Lists
Regulatory Name |
CAS Number/ 313 Category Code |
EPCRA 302 EHS TPQ |
EPCRA 304 EHS RQ |
CERCLA RQ |
EPCRA 313 TRI |
RCRA Code |
CAA 112(r) RMP TQ |
Phosphamidon |
13171-21-6 |
100 pounds |
100 pounds |
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(EPA List of Lists, 2022)
CISA Chemical Facility Anti-Terrorism Standards (CFATS)
No regulatory information available.
OSHA Process Safety Management (PSM) Standard List
No regulatory information available.
Alternate Chemical Names
- C 570
- 2-CHLORO-2- DIETHYLCARBAMOYL-1-METHYLVINYL DIMETHYL PHOSPHATE
- 2-CHLORO-2-DIETHYL CARBAMYL-1-METHYL VINYL DIMETHYL-PHOSPHATE
- 2-CHLORO-2-DIETHYLCARBAMOYL-1-METHYLVINYL DIMETHYLPHOSPHATE
- 2-CHLORO-2-DIETHYLCARBAMYL- 1-METHYLVINYL DIMETHYL PHOSPHATE
- 2-CHLORO-3-(DIETHYLAMINO)-1-METHYL-3-OXO-1- PROPENYL DIMETHYL PHOSPHATE
- 1-CHLORO-DIETHYLCARBAMOYL-1-PROPEN-2-YL DIMETHYL PHOSPHATE
- 2-CHLORO-N,N-DIETHYL-3-HYDROXYCROTONAMIDE DIMETHYL PHOSPHATE
- CROTONAMIDE, 2-CHLORO-N,N-DIETHYL-3-HYDROXY-, DIMETHYL PHOSPHATE
- DIMECRON
- DIMECRON 100
- DIMECRON 20
- DIMECRON 50
- DIMECRON-20
- DIMERCRON
- DIMETHYL 2-CHLORO-3-(DIETHYLAMINO)-1-METHYL-3-OXO-1-PROPENYLPHOSPHORATE
- DIMETHYL DIETHYLAMIDO-1-CHLOROCROTONYL (2) PHOSPHATE
- DIMETHYL PHOSPHATE OF 2-CHLORO-N,N-DIETHYL-3-HYDROXYCROTONAMIDE
- DIMETHYL-2-CHLORO-2-DIETHYLCARBAMOYL-1-METHYLVINYL PHOSPHATE
- DIXON
- ENT 25515
- FAMFOS
- MERKON
- ML 97
- N,N-DIETHYL 2-CHLORO-3-DIMETHYLPHOSPHATE CROTONAMIDE
- 2-(N,N-DIETHYLCARBAMOYL)-1-METHYLVINYL PHOSPHATE
- NCI-C0058
- NCI-C00588
- O,O-DIMETHYL-O-(2-CHLORO-2-(N,N-DIETHYLCARBAMOYL)-1-METHYLVINYL)PHOSPHATE
- OR 1191
- PHOSPHAMIDON
- PHOSPHAMIDONE
- PHOSPHORIC ACID, 2-CHLORO-3-(DIETHYLAMINO)-1-METHYL-3-OXO-1-PROPENYL DIMETHYL ESTER
- PHOSPHORIC ACID, DIMETHYL ESTER, ESTER WITH 2-CHLORO-N,N- DIETHYL-3-HYDROXYCROTONAMIDE
- PHOSPHORIC ACID, DIMETHYL ESTER, ESTER WITH 2-CHLORO-N,N-DIETHYL-3-HYDROXYCROTONAMIDE
- SUNDARAM 1975