MONOCROTOPHOS

Colorless crystals with a mild ester odor, commercial product is a reddish-brown solid. Used as a fast acting insecticide with both systemic and contact action against a wide range of pests on cotton, sugar cane, tobacco, potatoes, peanuts, tomatoes, and ornamentals. Very toxic.

none

Water soluble. Rapidly hydrolyzed.

Wear positive pressure breathing apparatus and full protective clothing. Container may explode in heat of fire. Toxic fumes evolved when heated to decomposition. Incompatible with alkaline compounds. Unstable in aqueous solution above pH 7.0; in low molecular weight alcohols and glycols. Stable in ketones and higher molecular weight alcohols and glycols. Stable when stored in glass or polyethylene containers. Relatively stable in sunlight. Keep away from temperatures above 80F; do not store below 70F. Corrosive to black iron, drum steel, stainless steel 304 and brass, but not to glass, aluminum, or stainless steel 316. (EPA, 1998)

Monocrotophos is an organophosphorus pesticide. It is a cholinesterase inhibitor and acts on the nervous system. Extremely toxic; probable oral lethal dose to humans 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70 kg (150 lb.) person. Repeated inhalation or skin contact with this material may, without symptoms, progressively increase susceptibility to poisoning. (EPA, 1998)

MONOCROTOPHOS is incompatible with the following: Metals, low molecular weight alcohols & glycols [Note: Corrosive to black iron, drum steel, stainless steel 304 & brass. Should be stored at 70-80°F.] (NIOSH, 2024). Incompatible with alkaline compounds.

• Amides and Imides
• Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
• Hydrocarbons, Aliphatic Unsaturated

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below.

• Dirt/Earth

Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Like other organophosphorus pesticides, move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.

Like other organophosphorus pesticides, extinguish with dry chemical, carbon dioxide, water spray, fog, or foam. (EPA, 1998)

As with other organophosphorus pesticides, do not touch spilled material; stop leak if you can do it without risk. Use water spray to reduce vapors.

Small spills: take up with sand or other noncombustible absorbent material and place into containers for later disposal.

Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area.

Large spills: dike far ahead of spill for later disposal. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Remove and isolate contaminated clothing at the site. (EPA, 1998)

Excerpt from NIOSH Pocket Guide for Monocrotophos:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises. (NIOSH, 2024)

No information available.

Note: Monocrotophos is a cholinesterase inhibitor.

Signs and Symptoms of Acute Monocrotophos Exposure: Acute exposure to monocrotophos may result in the following signs and symptoms: pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may also occur. The heart rate may decrease following oral exposure or increase following dermal exposure. Hypotension (low blood pressure) may occur, although hypertension (high blood pressure) is not uncommon. Chest pain may be noted. Dyspnea (shortness of breath) may lead to respiratory collapse. Giddiness is common.

Emergency Life-Support Procedures: Acute exposure to monocrotophos may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to monocrotophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self- exposure to monocrotophos.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of monocrotophos is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of monocrotophos may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

• APADRIN
• AZODRIN
• AZODRIN 202R
• AZODRIN 60
• AZODRIN INSECTICIDE
• BILOBRAN
• C 1414
• CIBA 1414
• CIS-1-METHYL-2-METHYL CARBAMOYL VINYL PHOSPHATE
• COROPHOS
• CRISODRIN
• CROTON 36
• CROTONAMIDE, 3-HYDROXY-N-METHYL-, DIMETHYLPHOSPHATE,(E)-
• 3-(DIMETHOXYPHOSPHINYLOXY) N-METHYL-CIS-CROTONAMIDE
• 3-(DIMETHOXYPHOSPHINYLOXY)-N-METHYL-CIS-CROTONAMIDE
• 3-(DIMETHOXYPHOSPHINYLOXY)-N-METHYLISOCROTONAMIDE
• DIMETHYL 1-METHYL-2-(METHYLCARBAMOYL)VINYL PHOSPHATE, CIS-
• DIMETHYL 2-METHYLCARBAMOYL-1- METHYLVINYL PHOSPHATE
• DIMETHYL PHOSPHATE ESTER OF 3-HYDROXY-N-METHYL-CIS- CROTONAMIDE
• DIMETHYL PHOSPHATE OF 3-HYDROXY-N-METHYL-CIS-CROTONAMIDE
• (E)-DIMETHYL 1-METHYL-3-(METHYLAMINO)-3-OXO-1-PROPENYL PHOSPHATE
• (E)-PHOSPHORIC ACID DIMETHYL ESTER, ESTER WITH 3-HYDROXY-N-METHYLCROTONAMIDE
• ENT 27,129
• 3-HYDROXY-N- METHYLCROTONAMIDE DIMETHYL PHOSPHATE
• 3-HYDROXY-N-METHYL-CIS-CROTONAMIDE DIMETHYL PHOSPHATE
• 3-HYDROXY-N-METHYLCROTONAMIDE DIMETHYLPHOSPHATE
• MONICIL
• MONOCIL
• MONOCIL 40
• MONOCOS
• MONOCRON
• MONOCROTOPHOS
• MONOSTAR
• N-DESMETHYL BIDRIN
• N-METHYL BIDRIN
• NUVACRON
• NUVACRON 20
• NUVACRON 36SL
• PARRYFOS
• PHOSPHORIC ACID, DIMETHYL 1-METHYL-3-(METHYLAMINO)-3-OXO-1-PROPENYL ESTER, (E)-
• PHOSPHORIC ACID, DIMETHYL 1-METHYL-3-(METHYLAMINO)-3-OXO-1-PROPENYL ESTER,(E)-
• PHOSPHORIC ACID, DIMETHYL ESTER, ESTER WITH 3-HYDROXY-N- METHYLCROTONAMIDE,(E)-
• PHOSPHORIC ACID, DIMETHYL ESTER, ESTER WITH 3-HYDROXY-N-METHYLCROTONAMIDE, (E)-
• PHOSPHORIC ACID, DIMETHYL ESTER, ESTER WITH CIS-3- HYDROXY-N-METHYLCROTONAMIDE
• PHOSPHORIC ACID, DIMETHYL ESTER, ESTER WITH(E)-3-HYDROXY-N- METHYLCROTONAMIDE
• PILLARDRIN
• PLANTDRIN
• SD 9129
• SHELL SD 9129
• SUSVIN