ERGOCALCIFEROL

Odorless white crystals. Used as a dietary supplement and food additive. (EPA, 1998)

none

No rapid reaction with air. No rapid reaction with water.

Shows signs of decomposition when stored for a few days at room temperature. (EPA, 1998)

Ergocalciferol poisoning disturbs calcium metabolism and causes kidney damage. Ergocalciferol in a single acute ingestion presents no toxic hazards. Daily ingestion in excess of 5000 units/day in children or 7500 units/day in adults will produce toxic symptoms associated with hypervitaminosis D. Those with hypercalcemia are at a greater risk. (EPA, 1998)

Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

• Alcohols and Polyols
• Hydrocarbons, Aliphatic Unsaturated
• Conjugated Dienes

Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below.

• Cellulose-Based Absorbents
• Dirt/Earth

Excerpt from 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

(Non-Specific -- Medicines, n.o.s.) Move container from fire area if you can do so without risk. Spray cooling water on containers that are exposed to flames until well after fire is out.

(Non-Specific -- Medicines, n.o.s.) Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam. (EPA, 1998)

(Non-Specific -- Medicines, n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Shut off ignition sources; no flares, smoking or flames in hazard area. Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch spilled material.

Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal.

Large spills: dike far ahead of spill for later disposal. (EPA, 1998)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

No information available.

Note: Emesis, activated charcoal, and cathartics are seldom necessary with acute ingestion unless extremely large amounts are ingested (more than 100 times the Recommended Daily Allowance for Vitamin D2).

Signs and Symptoms of Acute Ergocalciferol Exposure: Signs and symptoms of acute exposure to ergocalciferol may include the following: thirst, itching, fatigue, muscular weakness, nervousness, headache, nausea, vomiting, and diarrhea. Excessive urination, kidney impairment, and hypertension (high blood pressure) may be noted.

Emergency Life-Support Procedures: Acute exposure to ergocalciferol may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to ergocalciferol.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to ergocalciferol.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of ergocalciferol is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age. Warning: Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4. The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

• ACTIVATED ERGOSTEROL
• BUCO-D
• CALCIFEROL
• CALCIFERON 2
• CONDACAPS
• CONDOCAPS
• CONDOL
• CRTRON
• CRYSTALLINA
• CYCLOHEXANOL, 4-METHYLENE-3-[2-[TETRAHYDRO-7A-METHYL-1-(1,4,5-TRIMETHYL-2-HEXENYL)-4(3AH)-INDANYLIDENE]ETHYLIDENE]-
• D-ARTHIN
• D-TRACETTEN
• DARAL
• DAVITAMON D
• DAVITIN
• DE-RAT CONCENTRATE
• DECAPS
• DEE-OSTEROL
• DEE-RON
• DEE-RONAL
• DEE-ROUAL
• DELTALIN
• DERATOL
• DETALUP
• DIACTOL
• DIVIT URTO
• DORAL
• DRISDOL
• ERGOCALCIFEROL
• ERGORONE
• ERGOSTEROL ACTIVATED
• ERGOSTEROL, IRRADIATED
• ERTRON
• FORTODYL
• GELTABS
• HI-DERATOL
• INFRON
• IRRADIATED ERGOSTA-5,7,22-TRIEN- 3-BETA-OL
• IRRADIATED ERGOSTEROL
• METADEE
• MINA D2
• MULSIFEROL
• MYKOSTIN
• OLEOVITAMIN D
• OLEOVITAMIN D2
• OSTELIN
• RADIOSTOL
• RADSTERIN
• RODINE C
• 9,10-SECOERGOSTA-5,7,10(19),22-TETRAEN-3-BETA-OL
• 9,10-SECOERGOSTA-5,7,10(19),22-TETRAEN-3-OL,(3-BETA,5Z,7E,22E)-
• SHOCK-FEROL
• VIOSTEROL
• VITAMIN D2
• VITAVEL-D