DIETHYLCARBAMAZINE CITRATE

Crystalline solid, scored white tablets. Used against filariasis in man and animals. (EPA, 1998)

none

No rapid reaction with air. No rapid reaction with water.

When heated to decomposition, it emits toxic fumes of nitrogen oxides. Avoid decomposing heat. (EPA, 1998)

(Non-Specific -- Drugs, n.o.s.) May be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating or poisonous gases. Runoff from fire control or dilution water may cause pollution. The average adult man tolerates a single dose of 1.5 gm without ill effects. (EPA, 1998)

No information available.

• Alcohols and Polyols
• Amides and Imides
• Amines, Phosphines, and Pyridines

Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below.

• Cellulose-Based Absorbents
• Mineral-Based & Clay-Based Absorbents

Excerpt from 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Excerpt from 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

SMALL FIRE: Dry chemical, CO2 or water spray.

LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2020)

(Non-Specific -- Drugs, n.o.s.) Shut off ignition sources; no flares, smoking or flames in hazard area. Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch spilled material.

Small spills: take up with sand or other noncombustible absorbent material and place into containers for later disposal.

Large spills: dike far ahead of spill for later disposal. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. (EPA, 1998)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

No information available.

Warning: Effects may be delayed up to 16 hours. Caution is advised.

Signs and Symptoms of Diethylcarbamazine Citrate Exposure: Signs and symptoms of acute diethylcarbamazine citrate exposure may include the following: headache, nausea, vomiting, weakness, tachycardia (rapid pulse), hypotension, rapid breathing, mild fever, amd skin rash. Muscle tremors, weakness, and convulsions may also occur. An allergic reaction may occur about 16 hours after the initial exposure.

Emergency Life-Support Procedures: Acute exposure to diethylcarbamazine citrate may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to diethylcarbamazine citrate.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to diethylcarbamazine citrate.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of diethylcarbamazine citrate is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age.Warning: Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3 1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

• BANOCIDE
• CARICIDE
• CARITROL
• CYPIP
• DICAROCIDE
• DIETHYLCARBAMAZANE CITRATE
• DIETHYLCARBAMAZINE ACID CITRATE
• DIETHYLCARBAMAZINE CITRATE
• DIETHYLCARBAMAZINE HYDROGEN CITRATE
• 1-DIETHYLCARBAMOYL-4-METHYLPIPERAZINE DIHYDROGEN CITRATE
• DIROCIDE
• DITRAZIN
• DITRAZIN CITRATE
• DITRAZINE
• ETHODRYL CITRATE
• ETHYLAMINOAZINE CITRATE
• FILAZINE
• FRANOCIDE
• FRANOZAN
• HETRAZAN
• LOXURAN
• 1-METHYL-4-DIETHYLCARBAMOYLPIPERAZINE CITRATE
• N,N-DIETHYL-4-METHYL-1-PIPERAZINECARBOXAMIDE CITRATE
• N,N-DIETHYL-4-METHYL-1-PIPERAZINECARBOXAMIDE DIHYDROGEN CITRATE
• 1-PIPERAZINECARBOXAMIDE, N,N-DIETHYL-4-METHYL-, 2-HYDROXY-1,2,3-PROPANETRI- CARBOXYLATE
• 1-PIPERAZINECARBOXAMIDE, N,N-DIETHYL-4-METHYL-, CITRATE (1:1)
• 1-PIPERAZINECARBOXAMIDE, N,N-DIETHYL-4-METHYL-, CITRATE(1:1)