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Chemical Datasheet
Chemical Identifiers
CAS Number |
UN/NA Number |
DOT Hazard Label |
USCG CHRIS Code |
- 1464-53-5 (mixed isomers)
- 298-18-0 (D,L- mixed isomers)
- 30031-64-2 (L- isomer)
- 564-00-1 (meso- isomer)
|
|
- Poison Inhalation Hazard
- Flammable Liquid
- Corrosive
|
none
|
NIOSH Pocket Guide |
International Chem Safety Card |
none
|
none
|
NFPA 704
data unavailable
General Description
Colorless liquid. Used in curing polymers; crosslinking textile fibers and to prevent spoilage. (EPA, 1998)
Hazards
Reactivity Alerts
- Highly Flammable
- Polymerizable
Air & Water Reactions
Highly Flammable
Fire Hazard
When heated to decomposition it emits acrid smoke and irritating fumes. (EPA, 1998)
Health Hazard
Severe skin and eye irritant. Accidental minor exposure caused swelling of the eyelids, upper respiratory tract irritation and painful eye irritation 6 hours after exposure.
NOTE: The dl- and meso-forms (CAS Registry Numbers 298-18-0 and 564-00-1, respectively) as well as the L(-) form (CAS Registry Number 30031-64-2) have all been determined to be positive animal carcinogens. (EPA, 1998)
Reactivity Profile
Epoxides, such as DIEPOXYBUTANE, are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.
Belongs to the Following Reactive Group(s)
- Epoxides
- Polymerizable Compounds
Potentially Incompatible Absorbents
Use caution: Liquids with this reactive group classification have been
known to react with the
absorbents
listed below.
- Mineral-Based & Clay-Based Absorbents
- Dirt/Earth
Response Recommendations
Isolation and Evacuation
Excerpt from 131
[Flammable Liquids - Toxic]:
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.
SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 3489 datasheet.
FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)
Firefighting
Excerpt from 131
[Flammable Liquids - Toxic]:
CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient. CAUTION: Methanol (UN1230) will burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.).
SMALL FIRE: Dry chemical, CO2, water spray or alcohol-resistant foam.
LARGE FIRE: Water spray, fog or alcohol-resistant foam. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal. Avoid aiming straight or solid streams directly onto the product.
FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2020)
Non-Fire Response
Do not touch spilled material. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Warning: Effects may be delayed. Caution is advised.
Signs and Symptoms of Diepoxybutane Exposure: Acute exposure to diepoxybutane may produce severe irritation to skin, eyes, and gastrointestinal tract. Swelling of the eyelids may be noted. Respiratory signs may include irritation of the upper respiratory tract, which may progress to pulmonary edema.
Emergency Life-Support Procedures: Acute exposure to diepoxybutane may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to diepoxybutane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to diepoxybutane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert.
6. Transport to a health care facility. (EPA, 1998)
Physical Properties
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: data unavailable
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity:
1.113
at 64.4°F
(EPA, 1998)
- Denser than water; will sink
Boiling Point:
280°F
at 760 mmHg
(EPA, 1998)
Molecular Weight:
86.1
(EPA, 1998)
Water Solubility: data unavailable
Ionization Energy/Potential: data unavailable
IDLH: data unavailable
AEGLs (Acute Exposure Guideline Levels)
No AEGL information available.
ERPGs (Emergency Response Planning Guidelines)
No ERPG information available.
PACs (Protective Action Criteria)
Chemical |
PAC-1 |
PAC-2 |
PAC-3 |
Bioxirane, 2,2'-; (1,2:3,4-Diepoxybutane) (1464-53-5)
|
0.091 ppm |
1 ppm |
4 ppm |
(DOE, 2018)
Regulatory Information
EPA Consolidated List of Lists
Regulatory Name |
CAS Number/ 313 Category Code |
EPCRA 302 EHS TPQ |
EPCRA 304 EHS RQ |
CERCLA RQ |
EPCRA 313 TRI |
RCRA Code |
CAA 112(r) RMP TQ |
2,2'-Bioxirane |
1464-53-5 |
500 pounds |
10 pounds |
10 pounds |
X |
U085 |
|
Diepoxybutane |
1464-53-5 |
500 pounds |
10 pounds |
10 pounds |
313 |
U085 |
|
(EPA List of Lists, 2022)
CISA Chemical Facility Anti-Terrorism Standards (CFATS)
No regulatory information available.
OSHA Process Safety Management (PSM) Standard List
No regulatory information available.
Alternate Chemical Names
- 1,1'-BI(ETHYLENE OXIDE)
- BIOXIRAN
- BIOXIRANE
- 2,2'-BIOXIRANE
- 1,1'-BI[ETHYLENE OXIDE]
- BUTADIENE DIEPOXIDE
- 1,3-BUTADIENE DIEPOXIDE
- BUTADIENE DIOXIDE
- BUTANE DIEPOXIDE
- BUTANE, 1,2:3,4-DIEPOXY-
- DEB
- DIEPOXYBUTANE
- 1,2:3,4-DIEPOXYBUTANE
- 1,2:3,4- DIEPOXYBUTANE
- 2,4-DIEPOXYBUTANE
- DIOXYBUTADIENE
- ENT-26592
- ERYTHRITOL ANHYDRIDE
- NSC 629
- THREITOL, 1,2:3,4-DIANHYDRO-