CHLORDANE

It is a solid when pure, however, it is often formulated as a solution in organic solvents which may be flammable. Generally denser than water and insoluble in water. Vapors heavier than air. Toxic by inhalation, ingestion, or skin absorption. Formerly used as a pesticide but it has been banned in the US since 1988.

• Highly Flammable

Solutions of this material in organic solvents are often highly flammable. Insoluble in water.

Flammable/combustible material; may be ignited by heat, sparks or flames. Vapors may travel to a source of ignition and flash back. Run-off to sewers may create fire or explosion hazard. Containers may explode in heat of fire. Vapors are toxic indoors and outdoors. Chlordane degrades under natural environmental conditions to photoisomers, such as photo-cis- chlordane, which are more toxic to certain animals than chlordane and also showed higher bioaccumulation. Loses chlorine in presence of alkaline reagents; should not be formulated with any solvent, carrier, diluent or emulsifier which has alkaline reaction. (EPA, 1998)

Fatal oral dose to adult humans is between 6 and 60 g with onset of symptoms within 45 minutes to several hours after ingestion, although symptoms have occurred following very small doses either orally or by skin exposure. Some reports of delayed development of liver disease, blood disorders and upset stomach. Chlordane is considered to be borderline between a moderately and highly toxic substance. (EPA, 1998)

CHLORDANE is a chlorinated cyclodiene (unsaturated hydrocarbon). Decomposes in base. Corrosive to iron and zinc. Can react with strong oxidizing agents. Attack some plastics, rubbers and coatings (NTP, 1992).

• Halogenated Organic Compounds
• Hydrocarbons, Aliphatic Unsaturated

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below.

• Dirt/Earth

Excerpt from 131 [Flammable Liquids - Toxic]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Isolate hazard area and deny entry. Stay upwind. Wear positive pressure breathing apparatus and special protective clothing. Isolate for 1/2-mile in all directions if tank car or truck is involved in the fire.

Small fires: dry chemical, carbon dioxide, water spray, and foam. Large fires: water spray, fog, or foam. Move containers from fire area if it can be done without risk. Cool containers that are exposed to flames with water from the side until well after fire is out. (EPA, 1998)

Excerpt from 131 [Flammable Liquids - Toxic]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors.

SMALL SPILL: Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2020)

Excerpt from NIOSH Pocket Guide for Chlordane:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.

Provide:
• EYEWASH - Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substances; this is irrespective of the recommendation involving the wearing of eye protection.
• QUICK DRENCH - Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2023)

Normalized Breakthrough Times (in Minutes)

Chemical	CAS Number	State	QS	QC	SL	C3	TF	TP	RC	TK	RF
Chlordane (44%)	57-74-9	Liquid				>480
Chlordane (60-75%)	57-74-9	Liquid							>480	>480	>480

Special Warning from DuPont: Tychem® and Tyvek® fabrics should not be used around heat, flames, sparks or in potentially flammable or explosive environments. Only...

(DuPont, 2023)

Signs and Symptoms of Acute Chlordane exposure: Signs and symptoms of acute exposure to chlordane may be severe and include headache, dizziness, increased sensitivity to stimuli, agitation, nervousness, tremor, seizures, and coma. Convulsive episodes may alternate with periods of severe central nervous system depression. Nausea, vomiting, and diarrhea are common. Hypertension (high blood pressure), tachycardia (rapid heart rate), and cardiac arrhythmias (abnormal heart beating) may be noted. Respiratory depression may lead to respiratory arrest. Contact with the skin, eyes, and mucous membranes may result in redness and irritation. Victims often have an elevated temperature.

Emergency Life-Support Procedures: Acute exposure to chlordane may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to chlordane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to chlordane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas three times. Wash initially with soap and water, follow with an alcohol wash, then again with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of chlordane is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of chlordane may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3- 1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

• 1068
• ASPON-CHLORDANE
• BELT
• CD 68
• CHLOR KIL
• CHLORDAN
• CHLORDANE
• CHLORDANE (TECHNICAL MIXTURE AND METABOLITES)
• CHLORDANO
• CHLORINDAN
• CHLOROTOX
• CORODAN
• CORODANE
• CORTILAN-NEU
• DOWCHLOR
• ENT 9,932
• ENT 9932
• ENT-9932
• HCS 3260
• INTOX
• INTOX (INSECTICIDE)
• KYPCHLOR
• M 140
• M 410
• 4,7-METHANO-1H-INDENE, 1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A- HEXAHYDRO-
• 4,7-METHANOINDAN, 1,2,4,5,6,7,8,8-OCTACHLORO-3A,4,7,7A-TETRAHYDRO-
• 4,7-METHANOINDAN,
• NCI-C00099
• NIRAN
• OCTA-KLOR
• OCTACHLOR
• OCTACHLORDANE
• OCTACHLORO- 4,7-METHANOTETRAHYDROINDANE
• 1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A-HEXAHYDRO-4,7- METHANOINDENE
• 1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A-HEXAHYDRO-4,7-METHANOINDENE
• 1,2,4,5,6,7,8,8-OCTACHLORO-3A,4,7,7A-HEXAHYDRO-4,7-METHYLENE INDANE
• 1,2,4,5,6,7,8,8-OCTACHLORO-3A,4,7,7A-TETRAHYDRO-4,7-METHANOINDANE
• OCTACHLORO-4,7-METHANOHYDROINDANE
• OCTACHLORO-4,7-METHANOTETRAHYDROINDANE
• OCTACHLORODIHYDRODICYCLOPENTADIENE
• OKTATERR
• ORTHO-KLOR
• STARCHLOR
• SYDANE
• SYNKLOR
• TAT CHLOR 4
• TECHNICAL CHLORDANE
• TERMEX
• TOPICLOR
• TOXICHLOR
• UNEXAN-KOEDER
• VELSICOL 1068