DIETHYL SULFATE

Diamond	Hazard	Value	Description
1 3 1	Health	3	Can cause serious or permanent injury.
	Flammability	1	Must be preheated before ignition can occur.
	Instability	1	Normally stable but can become unstable at elevated temperatures and pressures.
	Special

A clear colorless liquid with a peppermint odor. Burns, though may be difficult to ignite. Corrosive to metals and tissue. It is a potent alkylating agent. Flash point is 104°C (219°F) [Aldrich MSDS].

• Water-Reactive

Combustible. Slowly reacts with water to form ethyl alcohol, a flammable liquid, and ethyl sulfate, with eventual conversion to sulfuric acid.

Special Hazards of Combustion Products: Highly toxic fumes contaning sulfur oxides may be generated along with thermal decomposition products such as ethyl ether and ethylene. Sulfuric acid may be produced in the presence of moisture.

Behavior in Fire: It burns to yield highly, toxic sulfur oxides. Above 100°C, it undergoes thermal decomposition to yield ethyl ether, ethylene and sulfur oxides which may cause an explosion in closed containers or confined spaces. (USCG, 1999)

May be fatal if inhaled, swallowed or absorbed through skin. Inhalation causes nausea and vomiting. Causes burns to skin and eyes. Ingestion may cause nausea, vomiting abdominal pain and collapse. (USCG, 1999)

The presence of moisture in a metal container of DIETHYL SULFATE caused the formation of sulfuric acid which reacts with the metal to release hydrogen which pressurized and exploded the container [Chem. Abst. 28:2908(1934)].

• Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

No information available.

Excerpt from 152 [Substances - Toxic (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Excerpt from 152 [Substances - Toxic (Combustible)]:

SMALL FIRE: Dry chemical, CO2 or water spray.

LARGE FIRE: Water spray, fog or regular foam. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal. Avoid aiming straight or solid streams directly onto the product.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2020)

Excerpt from 152 [Substances - Toxic (Combustible)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2020)

Wear positive pressure breathing apparatus and special protective clothing. (USCG, 1999)

Normalized Breakthrough Times (in Minutes)

Chemical	CAS Number	State	QS	QC	SL	C3	TF	TP	RC	TK	RF
Diethyl sulfate	64-67-5	Liquid				>480	>480	>480		>480
Sulfuric acid diethyl ester	64-67-5	Liquid				>480	>480	>480		>480

Special Warning from DuPont: Tychem® and Tyvek® fabrics should not be used around heat, flames, sparks or in potentially flammable or explosive environments. Only...

(DuPont, 2023)

INHHALATION: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

EYES OR SKIN: Irrigate with running water for at least 15 min.; hold eyelids open if neccessary. Consult an ophthamologist immediately. Wash skin with soap and water. Speed in removing material from skin is of extreme importance. Remove contaminated clothing and shoes at the site. Keep victim quiet and maintain normal body temperature. Effects may be delayed; keep victim under observation.

INGESTION: If victim is conscious, give victim two glasses of water and have victim induce vomiting. (USCG, 1999)

• DES
• DIETHYL SULFATE
• DIETHYL SULPHATE
• ETHYL SULFATE
• SULFURIC ACID, DIETHYL ESTER