1,3-DICHLOROACETONE

A crystalline solid. Denser than water and insoluble in water. Inhalation of dust or powder may cause adverse health reactions.

none

Insoluble in water.

When heated to decomposition, it emits highly toxic fumes of chlorides. This material may burn but does not ignite readily. Container may explode in heat of fire. (EPA, 1998)

It may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. (EPA, 1998)

A halogenated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

• Halogenated Organic Compounds
• Ketones

No information available.

Excerpt from 153 [Substances - Toxic and/or Corrosive (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site. If water pollution occurs, notify appropriate authorities.

For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. (EPA, 1998)

Excerpt from 153 [Substances - Toxic and/or Corrosive (Combustible)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2020)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

Normalized Breakthrough Times (in Minutes)

Chemical	CAS Number	State	QS	QC	SL	C3	TF	TP	RC	TK	RF
Dichloro -2-propanone, 1,3- (45°C, molten)	534-07-6	Liquid					>480	>480
Dichloro -2-propanone, 1,3- (95% at 40°C, molten)	534-07-6	Liquid								>480
Dichloro acetone, 1,3- (45°C, molten)	534-07-6	Liquid					>480	>480
Dichloro acetone, 1,3- (95% at 40°C, molten)	534-07-6	Liquid								>480

Special Warning from DuPont: Tychem® and Tyvek® fabrics should not be used around heat, flames, sparks or in potentially flammable or explosive environments. Only...

(DuPont, 2023)

Warning: Bis(chloromethyl) ketone may be fatal if inhaled, swallowed, or absorbed through skin.

Signs and Symptoms of Bis(chloromethyl) Ketone Exposure: Signs and symptoms of acute exposure to bis(chloromethyl) ketone include burning of the skin and mucous membrane surfaces. Eye exposure may result in pain, lacrimation (tearing), and corneal damage. Tachycardia (rapid heart beat), hypothermia (low body temperature), nausea and vomiting may also be noted. Inhalation exposure may produce respiratory depression, dyspnea (difficult or labored breathing) and gasping. Skin exposure to the liquid or vapor may result in dermatitis and paresthesia (burning or prickling sensation) of affected areas. CNS depression may be noted following inhalation. Headache, dizziness, fainting, tremor, and coma are also potential symptoms.

Emergency Life-Support Procedures: Acute exposure to bis(chloromethyl) ketone may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to bis(chloromethyl) ketone.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to bis(chloromethyl) ketone.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. DO NOT induce vomiting.
4. Immediately dilute with milk or water in the non-respiratory compromised patient. Give children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert.
5. Transport to a health care facility. (EPA, 1998)

• ALPHA,ALPHA'-DICHLOROACETONE
• ALPHA,GAMMA-DICHLOROACETONE
• BIS(CHLOROMETHYL) KETONE
• 1,3-DICHLORO-2-PROPANONE
• 1,3-DICHLOROACETONE
• 2-PROPANONE, 1,3-DICHLORO-
• SYM-DICHLOROACETONE