VITAMIN A

PHYSICAL DESCRIPTION: Yellow crystals or orange solid. Practically water insoluble. (NTP, 1992)

none

Practically water insoluble.

Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

SYMPTOMS: Symptoms of chronic overdose include fatigue, malaise, lethargy, abdominal discomfort, anorexia and vomiting. Skeletal effects include slow growth, hard tender cortical thickening over the radius and tibia, migratory arthralgia and premature closing of the epiphysis. Central nervous system effects include irritability, headache and increased intracranial pressure as manifested by bulging fontanels, papilledema and exophthalmos. Dermatologic effects include fissures of the lips, drying and cracking of the skin, alopecia, scaling, massive desquamation and increased pigmentation. Systemic effects include hypomenorrhea, hepatosplenomegaly, jaundice, leukopenia and vitamin A plasma level over 1200 units. Other effects include painful nodular periosteal swelling, osteoporosis, itching, skin eruptions, ulcerations, drowsiness, alopecia, liver enlargement, diplopia and papilledema.

ACUTE/CHRONIC HAZARDS: When heated to decomposition, this compound emits toxic fumes of carbon monoxide and carbon dioxide. It is harmful if swallowed, inhaled or absorbed through the skin. (NTP, 1992)

VITAMIN A is light sensitive. Also air sensitive and heat sensitive. Reacts with strong oxidizing agents. Also can react with acids (NTP, 1992). Can react exothermically with reducing agents to release hydrogen gas.

• Alcohols and Polyols
• Hydrocarbons, Aliphatic Unsaturated
• Conjugated Dienes

Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below.

• Cellulose-Based Absorbents
• Dirt/Earth

No information available.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store it in a freezer. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

No information available.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. If symptoms (such as redness or irritation) develop, immediately transport the victim to a hospital.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

• ACON
• AFAXIN
• AGIOLAN
• (ALL-E)-
• ALL-TRANS-RETINOL
• ALL-TRANS-RETINYL ALCOHOL
• ALL-TRANS-VITAMIN A ALCOHOL
• ALPHALIN
• ALPHASTEROL
• ANATOLA
• ANATOLA A
• ANTI-INFECTIVE VITAMIN
• ANTIXEROPHTHALMIC VITAMIN
• AORAL
• APEXOL
• APOSTAVIT
• AQUASYNTH
• ATARS
• ATAV
• AVIBON
• AVITA
• AVITOL
• AXEROL
• AXEROPHTHOL
• BIOSTEROL
• CHOCOLA A
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2,4,6,8-NONATETRAEN-1-OL
• DISATABS TABS
• DOFSOL
• DOHYFRAL A
• EPITELIOL
• HI-A-VITA
• HYDROVIT A
• LARD FACTOR
• LPK
• MICROVIT A
• MYVPACK
• NIO-A-LET
• 2,4,6,8-NONATETRAEN-1-OL, 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-
• OLEOVITAMIN A
• OPHTHALAMIN
• PREPALIN
• PROVITAMIN A
• RETINOL
• RETROVITAMIN A
• ROVIMIX A 500
• TESTAVOL
• TRANS-RETINOL
• VAFLOL
• VAFOL
• VI-ALPHA
• VITAMIN A
• VITAMIN A ALCOHOL
• VITAMIN A1
• VITAMIN A1 ALCOHOL
• VITAVEL A
• VITPEX
• VOGAN
• VOGAN-NEU