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Chemical Datasheet

METHOXYFLURANE

3 - Combustible liquid (U.S.)

Chemical Identifiers

CAS Number UN/NA Number DOT Hazard Label USCG CHRIS Code
  • 76-38-0   (METHOXYFLURANE)
  • 1993
  • Combustible Liquid
none
NIOSH Pocket Guide International Chem Safety Card
Methoxyflurane
  • METHOXYFLURANE
NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: Clear colorless liquid with a sweet fruity odor. (NTP, 1992)

Hazards

Reactivity Alerts
none
Air & Water Reactions
Insoluble in water.
Fire Hazard
This chemical is combustible. (NTP, 1992)
Health Hazard
Excerpt from NIOSH Pocket Guide for Methoxyflurane:

Exposure Routes: Inhalation, ingestion, skin and/or eye contact

Symptoms: Irritation eyes; central nervous system depression, analgesia, anesthesia, convulsions, resp depression; liver, kidney injury; In Animals: reproductive, teratogenic effects

Target Organs: Eyes, central nervous system, liver, kidneys, reproductive system (NIOSH, 2023)
Reactivity Profile
METHOXYFLURANE may be sensitive to prolonged exposure to light.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

Response Recommendations

Isolation and Evacuation
Excerpt from 128 Polymerizable warning [Flammable Liquids (Water-Immiscible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)
Firefighting
Fires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should protect this material for prolonged exposure to light and store it under ambient temperatures. (NTP, 1992)
Protective Clothing
Excerpt from NIOSH Pocket Guide for Methoxyflurane:

Skin: No recommendation is made specifying the need for personal protective equipment for the body.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: No recommendation is made specifying the need for washing the substance from the skin (either immediately or at the end of the work shift).

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: No recommendation is made specifying the need for the worker to change clothing after the workshift. (NIOSH, 2023)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Physical Properties

Chemical Formula:
  • C3H4Cl2F2O
Flash Point: 145°F (NTP, 1992)
Lower Explosive Limit (LEL): 7 % at 176°F (NIOSH, 2023)
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: -31°F (NTP, 1992)
Vapor Pressure: 20 mmHg at 63.9°F ; 22.5 mmHg at 68°F (NTP, 1992)
Vapor Density (Relative to Air): data unavailable
Specific Gravity: 1.426 at 68°F (NTP, 1992) - Denser than water; will sink
Boiling Point: 220.3°F at 760 mmHg (NTP, 1992)
Molecular Weight: 164.97 (NTP, 1992)
Water Solubility: less than 1 mg/mL at 66°F (NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

Regulatory Information

EPA Consolidated List of Lists

No regulatory information available.

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

Alternate Chemical Names