2-HYDROXYBENZAMIDE

PHYSICAL DESCRIPTION: Odorless white or slightly pink crystals. Bitter taste, leaves a sensation of warmth on the tongue. pH (saturated aqueous solution at 82°F) about 5. Sublimation begins at the melting point. (NTP, 1992)

none

It darkens on exposure to air. (NTP, 1992). Insoluble in water.

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

SYMPTOMS: Symptoms of exposure to this compound include dizziness, drowsiness, nausea, vomiting, epigastric distress, allergic reactions and blood dyscrasias. It can cause central nervous depression, hypotension and respiratory arrest. This compound may greatly potentiate the hepatic toxicity of acetaminophen. It may also cause hyperpnea, renal failure, prolonged bleeding time, a mild burning pain in the mouth, throat and abdomen, lethargy, tinnitus hearing loss, excitability, delirium, fever, sweating, dehydration, incoordination, restlessness, ecchymoses, coma, convulsions, cyanosis, oliguria, uremia, pulmonary edema, gastric ulcer, weight loss and mental deterioration. Other symptoms may include skin eruptions, headache, difficulty in hearing, dimness of vision, lassitude and hyperventilation.

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides. (NTP, 1992)

2-HYDROXYBENZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). This chemical may be sensitive to prolonged exposure to light. (NTP, 1992)

• Amides and Imides
• Phenols and Cresols

No information available.

No information available.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

No information available.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

• ACKET
• AFKO-SAL
• ALGAMON
• ALGIAMIDA
• ALLEVIN
• AMID-SAL
• AMIDOSAL
• ANAMID
• BENESAL
• BENZAMIDE, 2-HYDROXY-
• BENZAMIDE, O-HYDROXY-
• 2-CARBAMOYLPHENOL
• 2-CARBOXAMIDOPHENOL
• CETAMIDE
• CIDAL
• CYMIDON
• DOLOMIDE
• DROPSPRIN
• H.P. 34
• 2-HYDROXYBENZAMIDE
• LIQUIPRIN
• MORSARINAS
• NOVECYL
• O-HYDROXYBENZAMIDE
• OHB
• ORAMID
• PANITHAL
• RASPBERIN
• SALAMID
• SALAMIDE
• SALIAMID
• SALIAMIN
• SALICIM
• SALICYLAMID
• SALICYLAMIDE
• SALICYLAMIDE, 2-HYDROXYBENZOICACIDAMIDE
• SALICYLIC ACID AMIDE
• SALIPUR
• SALIZELL
• SALRIN
• SALYMID
• SAM
• SAMID
• SERRAMIDA
• SR 4326
• URTOSAL