CHLOROTHIAZIDE

PHYSICAL DESCRIPTION: Crystals; white powder. (NTP, 1992)

none

Insoluble in water.

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

SYMPTOMS: Symptoms of exposure to this compound may include skin and mucous membrane irritation; pancreatitis, depression of the formed elements of the blood; purpura, photosensitive dermatitis, necrotizing vasculitis, hyperglycemia, aggravation of diabetes mellitus; exacerbation of renal and/or hepatic insufficiency; lethargy, potassium loss, hyperglycemia, hyperuricemia, coma, chloride loss, lethargy, muscle cramps, acidosis, skin rash, salivary gland obstruction, psychosis, convulsions, leukopenia, jaundice, excessive amount of calcium in the blood, acute glomerulonephritis, anorexia, nausea, vomiting, cramping, diarrhea, dizziness, constipation, vertigo, paresthesis, headache, xanthopsia, hemolytic anemia, urticuria, fever, respiratory distress, including pneumonitis and pulmonary edema, anaphylactic reactions, glycosuria, muscle spasm, weakness, transient blurred vision and restlessness.

ACUTE/CHRONIC HAZARDS: This compound may cause skin and mucous membrane irritation. When heated to decomposition it emits very toxic fumes. (NTP, 1992)

Alkaline aqueous solutions will decompose on standing or heating (NTP, 1992).

• Amines, Phosphines, and Pyridines
• Sulfonates, Phosphonates, and Thiophosphonates, Organic
• Aryl Halides

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below.

• Mineral-Based & Clay-Based Absorbents

No information available.

Fires involving this material can be controlled with a carbon dioxide, dry chemical or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then dampen the solid spill material with toluene, then transfer the dampened material to a suitable container. Use absorbent paper dampened with toluene to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

No information available.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

• ALURENE
• CHLORIAZID
• 6-CHLORO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
• 6-CHLORO-7-SULFAMOYL-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE
• 6-CHLORO-7-SULFAMYL-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE
• CHLOROSAL
• CHLOROTHIAZID
• CHLOROTHIAZIDE
• CHLORTHIAZIDE
• CHLORURIT
• CHLOTRIDE
• CHLROSAL
• CLOTRIDE
• CT
• DIURESAL
• DIURIL
• DIURILIX
• DIURITE
• DIUTRID
• EXURIL
• FLUMEN
• MINZIL
• NEO-DEMA
• RO-CHLOROZIDE
• SALISAN
• SALUNIL
• SALURETIL
• SALURIC
• SK-CHLOROTHIAZIDE
• THIAZIDE
• URINEX
• WARDUZIDE
• YADALAN
• YADULAN