TRIMETHYLCHLOROSILANE

Diamond	Hazard	Value	Description
3 3 2 W	Health	3	Can cause serious or permanent injury.
	Flammability	3	Can be ignited under almost all ambient temperature conditions.
	Instability	2	Readily undergoes violent chemical changes at elevated temperatures and pressures.
	Special	W	Reacts violently or explosively with water.

A colorless fuming liquid with a pungent odor. Boiling point 135°F, Flash point -18°F. Density 0.854 g / cm3. The vapor and liquid may cause burns. Vapors are heavier than air.

• Highly Flammable
• Water-Reactive
• Air-Reactive

Highly flammable. Fumes in air. Reacts vigorously and exothermically with water. Products of the reaction include hydrogen chloride. The heat may be sufficient to ignite nearby combustible materials.

Trimethylchlorosilane reacts vigorously with water to generate gaseous HCl. Based on a scenario where the chemical is spilled into an excess of water (at least 5 fold excess of water), half of the maximum theoretical yield of Hydrogen Chloride gas will be created in 1.3 minutes. Experimental details are in the following: "Development of the Table of Initial Isolation and Protective Distances for the 2008 Emergency Response Guidebook", ANL/DIS-09-2, D.F. Brown, H.M. Hartmann, W.A. Freeman, and W.D. Haney, Argonne National Laboratory, Argonne, Illinois, June 2009.

Violent reaction with water. Toxic and irritating hydrogen chloride and phosgene may be formed in fires. Difficult to extinguish, re-ignition may occur. Flashback along vapor trail may occur. Containers may explode in fire. Vapor may explode if ignited in enclosed area. When heated to decomposition or on contact with acids or acid fumes, chloride fumes are emitted. Reacts with surface moisture, releasing hydrogen chloride, which will corrode common metals and form flammable hydrogen gas. Avoid contact with water; it readily hydrolyzes, liberating hydrochloric acid. Hazardous polymerization may not occur. (EPA, 1998)

Similar to other silanes. Toxicity is rated high for inhalation, ingestion and local irritation. May cause death or permanent injury after a very short exposure to small quantities. (EPA, 1998)

TRIMETHYLCHLOROSILANE reacts vigorously and exothermically with water to produce hydrogen chloride.

• Chlorosilanes

Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below.

• Cellulose-Based Absorbents
• Mineral-Based & Clay-Based Absorbents
• Dirt/Earth

Excerpt from ERG Guide 155 [Substances - Toxic and/or Corrosive (Flammable / Water-Sensitive)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 1298 datasheet.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Use acid-vapor-type respirator, rubber gloves, chemical worker's goggles, and other protective equipment as necessary to protect skin and eyes.

Extinguish with dry chemicals or carbon dioxide. Do not use water or foam. Cool exposed containers with water. Water spray, fog, or foam may be required to fight large fires. However, trimethylchlorosilane may react violently with water. Do not get water inside containers. (EPA, 1998)

Excerpt from ERG Guide 155 [Substances - Toxic and/or Corrosive (Flammable / Water-Sensitive)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor-suppressing foam may be used to reduce vapors. FOR CHLOROSILANES, use alcohol-resistant foam to reduce vapors. DO NOT GET WATER on spilled substance or inside containers. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal. (ERG, 2024)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

No information available.

Warning: In the presence of water, trimethylchlorosilane liberates hydrochloric acid, which is extremely corrosive. Caution is advised.

Signs and Symptoms of Acute Trimethylchlorosilane Exposure: Signs and symptoms of acute trimethylchlorosilane exposure may include increased salivation, intense thirst, difficulty swallowing, chills, pain, and shock. Oral, esophageal, and stomach burns are common. Vomitus generally has a coffee-ground appearance. Acute inhalation exposure may result in hoarseness, laryngitis, a feeling of suffocation, dyspnea (shortness of breath), choking, respiratory tract irritation, chest pain, and pulmonary edema. The potential for circulatory collapse is high following ingestion of trimethylchlorosilane. Sneezing, bleeding of the nose and gums, and ulceration of the nasal and oral mucosa may also occur. Renal toxicity has been observed in animals. If the eyes come in contact with trimethylchlorosilane, irritation, pain, swelling, corneal erosion, and blindness may result. Dermal exposure is generally followed by dermatitis (red, inflamed skin), severe burns, pain, and shock.

Emergency Life-Support Procedures: Acute exposure to trimethylchlorosilane may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to trimethylchlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. RUSH to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self- exposure to trimethylchlorosilane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas THOROUGHLY with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. RUSH to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Rinse mouth with large amounts of water. Inform victims not to swallow this water.
3. DO NOT induce vomiting or attempt to neutralize! 4 Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
5. Activated charcoal is of no value.
6. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert.
7. RUSH to a health care facility. (EPA, 1998)

• CHLOROTRIMETHYLSILANE
• CHLOROTRIMETHYLSILICANE
• KA 31
• MONOCHLOROTRIMETHYLSILANE
• MONOCHLOROTRIMETHYLSILICON
• SILANE, CHLOROTRIMETHYL-
• SILANE, TRIMETHYLCHLORO-
• SILICANE, CHLOROTRIMETHYL
• SILYLIUM, TRIMETHYL-, CHLORIDE
• TL 1163
• TRIMETHYL CHLOROSILANE
• TRIMETHYLCHLOROSILANE
• TRIMETHYLSILANE CHLORIDE
• TRIMETHYLSILICON CHLORIDE
• TRIMETHYLSILYL CHLORIDE
• TSL 8031