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Chemical Datasheet
Chemical Identifiers
CAS Number |
UN/NA Number |
DOT Hazard Label |
USCG CHRIS Code |
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none
|
data unavailable
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none
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NIOSH Pocket Guide |
International Chem Safety Card |
none
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none
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NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: Clear colorless liquid. Denser than water. (NTP, 1992)
Hazards
Reactivity Alerts
none
Air & Water Reactions
Water soluble.
Fire Hazard
This chemical is combustible. (NTP, 1992)
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, respiratory tract and mucous membranes, dermatitis, nausea, vomiting, central nervous system depression and fibrosis. It may cause decreased visual acuity. A related compound is corrosive to tissues.
ACUTE/CHRONIC HAZARDS: This compound is an irritant of the skin, eyes and mucous membranes. When heated to decomposition it emits toxic fumes of sulfur oxides. A similar compound is corrosive. (NTP, 1992)
Reactivity Profile
ETHYL METHANESULFONATE alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product (NTP, 1992).
Belongs to the Following Reactive Group(s)
- Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
- Sulfonates, Phosphonates, and Thiophosphonates, Organic
Potentially Incompatible Absorbents
No information available.
Response Recommendations
Isolation and Evacuation
No information available.
Firefighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
STORAGE PRECAUTIONS: You should store this chemical under refrigerated temperatures, and protect it from moisture. (NTP, 1992)
Protective Clothing
MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). Splash proof safety goggles should be worn while handling this chemical. Alternatively, a full face respirator, equipped as above, may be used to provide simultaneous eye and respiratory protection. (NTP, 1992)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
INGESTION: DO NOT INDUCE VOMITING. Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and, in addition, have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. Transport the victim IMMEDIATELY to a hospital.
OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)
Physical Properties
Flash Point:
212°F
(NTP, 1992)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: data unavailable
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity:
1.1452
at 72°F
(NTP, 1992)
- Denser than water; will sink
Boiling Point:
415 to 416°F
at 761 mmHg
(NTP, 1992)
Molecular Weight:
124.17
(NTP, 1992)
Water Solubility:
50 to 100 mg/mL
at 81°F
(NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable
AEGLs (Acute Exposure Guideline Levels)
No AEGL information available.
ERPGs (Emergency Response Planning Guidelines)
No ERPG information available.
PACs (Protective Action Criteria)
Chemical |
PAC-1 |
PAC-2 |
PAC-3 |
Methanesulfonic acid, ethyl ester; (Ethyl methanesulfonate) (62-50-0)
|
2.1 mg/m3 |
23 mg/m3 |
140 mg/m3 |
(DOE, 2024)
Regulatory Information
EPA Consolidated List of Lists
Regulatory Name |
CAS Number/ 313 Category Code |
EPCRA 302 EHS TPQ |
EPCRA 304 EHS RQ |
CERCLA RQ |
EPCRA 313 TRI |
RCRA Code |
CAA 112(r) RMP TQ |
Ethyl methanesulfonate |
62-50-0 |
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1 pound |
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U119 |
|
(EPA List of Lists, 2024)
CISA Chemical Facility Anti-Terrorism Standards (CFATS)
No regulatory information available.
OSHA Process Safety Management (PSM) Standard List
No regulatory information available.
Alternate Chemical Names
- EMS
- ENT 26396
- ETHYL ESTER OF METHANESULFONIC ACID
- ETHYL ESTER OF METHANESULPHONIC ACID
- ETHYL ESTER OF METHYLSULFONIC ACID
- ETHYL ESTER OF METHYLSULPHONIC ACID
- ETHYL MESYLATE
- ETHYL METHANESULFONATE
- ETHYL METHANESULPHONATE
- ETHYL METHANSULFONATE
- ETHYL METHANSULPHONATE
- HALF-MYLERAN
- METHANESULPHONIC ACID ETHYL ESTER
- METHYLSULFONIC ACID, ETHYL ESTER
- NSC 26805
- O-ETHYL METHYLSULFONATE