AMITROLE

PHYSICAL DESCRIPTION: Odorless white crystals or white powder. Bitter taste. Melting point 147-159°C. Sublimes undecomposed at reduced pressure. Used as a post-emergence herbicide.

none

Water soluble. Aqueous solutions are neutral. Dust may form an explosive mixture in air.

Literature sources indicate that this compound is non-combustible. (NTP, 1992)

Excerpt from NIOSH Pocket Guide for Amitrole:

Exposure Routes: Inhalation, ingestion, skin and/or eye contact

Symptoms: Irritation eyes, skin; dyspnea (breathing difficulty), muscle spasms, ataxia, anorexia, salivation, increased body temperature; lassitude (weakness, exhaustion), skin dryness, depression (thyroid function suppression)

Target Organs: Eyes, skin, thyroid

Cancer Site: [in animals: liver, thyroid & pituitary gland tumors] (NIOSH, 2023)

AMITROLE is a triazole derivative. The triazoles are a group that contain several derivatives that are highly explosive materials. They are sensitive to heat, friction, and impact. Sensitivity varies with the type substitution to the triazole ring. Metal chelated and halogen substitution of the triazole ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. AMITROLE forms chelates with some metals. It is corrosive to iron, copper and aluminum. Forms salts with most acids and alkalis. This compound is incompatible with strong oxidizers, strong acids, acid chlorides and acid anhydrides (NTP, 1992).

• Azo, Diazo, Azido, Hydrazine, and Azide Compounds
• Amines, Aromatic

No information available.

Excerpt from 171 [Substances (Low to Moderate Hazard)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Fires involving this chemical can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should keep this material in a tightly closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)

Excerpt from NIOSH Pocket Guide for Amitrole:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: DAILY - The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.

Provide:
• EYEWASH - Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substances; this is irrespective of the recommendation involving the wearing of eye protection.
• QUICK DRENCH - Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2023)

No information available.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)

• 3,A-T
• AMEROL
• AMINO TRIAZOLE WEEDKILLER 90
• 3-AMINO-1,2,4-TRIAZOLE
• 5-AMINO-1,2,4-TRIAZOLE
• 2-AMINO-1,3,4-TRIAZOLE
• 3-AMINO-1H-1,2,4-TRIAZOLE
• 5-AMINO-1H-1,2,4-TRIAZOLE
• 3-AMINO-S-TRIAZOLE
• AMINOTRIAZOL-SPRITZPULVER
• AMINOTRIAZOLE
• AMINOTRIAZOLE (PLANT REGULATOR)
• 2-AMINOTRIAZOLE
• 3-AMINOTRIAZOLE
• AMITOL
• AMITRIL
• AMITRIL T.L.
• AMITROL
• AMITROL 90
• AMITROL-T
• AMITROLE
• AMIZOL
• AMIZOL D
• AMIZOL DP NAU
• AMIZOL F
• AT
• AT LIQUID
• AT-90
• ATA
• ATA (AMINE)
• AZAPLANT
• AZAPLANT KOMBI
• AZOLAN
• AZOLE
• CAMPAPRIM A 1544
• CYTROL
• CYTROL AMITROLE-T
• CYTROLE
• DIUROL
• DIUROL 5030
• DOMATOL
• DOMATOL 88
• ELMASIL
• EMISOL
• EMISOL 50
• EMISOL F
• ENT 25445
• FENAMINE
• FENAVAR
• 1H-1,2,4-TRIAZOL-3-AMINE
• HERBIDAL TOTAL
• HERBIZOLE
• KLEER-LOT
• ORGA-414
• RADOXONE TL
• RAMIZOL
• S-TRIAZOLE, 3-AMINO-
• SIMAZOL
• SOLUTION CONCENTREE T271
• 2,3,5,6-TETRAAZABICYCLO[2.1.1]HEX-1-ENE
• TRIAZOLAMINE
• USAF XR-22
• VOROX
• VOROX AA
• VOROX AS
• WEEDAR ADS
• WEEDAR AT
• WEEDAZIN
• WEEDAZIN ARGINIT
• WEEDAZOL
• WEEDAZOL GP2
• WEEDAZOL SUPER
• WEEDAZOL T
• WEEDAZOL TL
• WEEDEX GRANULAT
• WEEDOCLOR
• X-ALL LIQUID