HALOTHANE

PHYSICAL DESCRIPTION: Clear colorless highly volatile liquid with a sweet chloroform-like odor. Density 1.875 g / cm3. Boiling point 122.4°F (50.2°C). Noncombustible.

none

Slightly water soluble.

Literature sources indicate that this chemical is nonflammable. (NTP, 1992)

Excerpt from NIOSH Pocket Guide for Halothane:

Exposure Routes: Inhalation, skin absorption, ingestion, skin and/or eye contact

Symptoms: Irritation eyes, skin, respiratory system; confusion, drowsiness, dizziness, nausea, analgesia, anesthesia; cardiac arrhythmias; liver, kidney damage; decreased audio-visual performance; In Animals: reproductive effects

Target Organs: Eyes, skin, respiratory system, cardiovascular system, central nervous system, liver, kidneys, reproductive system (NIOSH, 2023)

HALOTHANE is sensitive to exposure to light. Incompatible with oxidizing materials. Tarnishes or corrodes most metals, with the exception of chromium, nickel and titanium. When moisture is present, it attacks aluminum, brass and lead, but not copper. Contact causes rubber and some plastics to deteriorate rapidly. (NTP, 1992)

• Halogenated Organic Compounds
• Fluorinated Organic Compounds

No information available.

Excerpt from 171 [Substances (Low to Moderate Hazard)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should protect this material from exposure to light. Keep it away from oxidizing materials and store it under refrigerated temperatures. (NTP, 1992)

Excerpt from NIOSH Pocket Guide for Halothane:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: No recommendation is made specifying the need for the worker to change clothing after the workshift.

Provide: EYEWASH - Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substances; this is irrespective of the recommendation involving the wearing of eye protection. (NIOSH, 2023)

No information available.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. Volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

• ANESTAN
• 1-BROMO-1-CHLORO-2,2,2-TRIFLUOROETHANE
• 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE
• BROMOCHLOROTRIFLUOROETHANE
• CHALOTHANE
• FLUKTAN
• FLUOROTANE
• FLUOTHANE
• FREON 123B1
• FTOROTAN
• HALAN
• HALOTAN
• HALOTHANE
• (.+-.)-HALOTHANE
• HALSAN
• NARCOTAN
• NARCOTANE
• NARKOTAN
• R 123B1
• RHODIALOTHAN
• 2,2,2-TRIFLUORO-1-BROMO-1-CHLOROETHANE
• 2,2,2-TRIFLUORO-1-CHLORO-1-BROMOETHANE
• 1,1,1-TRIFLUORO-2,2-CHLOROBROMOETHANE
• 1,1,1-TRIFLUORO-2-BROMO-2-CHLOROETHANE
• 1,1,1-TRIFLUORO-2-CHLORO-2-BROMOETHANE