Reactive Group Datasheet

Amides and Imides, Organic

What are reactive groups?

Reactive groups are categories of chemicals that typically react in similar ways because they are similar in their chemical structure. Each substance with a chemical datasheet has been assigned to one or more reactive groups, and CAMEO Chemicals uses the reactive group assignments to make its reactivity predictions. More Info...

If you can't find a chemical in the database--but you know what reactive group it belongs in--you can add the reactive group to MyChemicals instead in order to see the reactivity predictions.

There are 278 chemical datasheets assigned to this reactive group.

Description

Flammability

Compounds in this group are combustible. The products of their combustion include noxious NOx.

Reactivity

Organic amides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generate mixed oxides of nitrogen (NOx).

Toxicity

Low to moderate. They act by ingestion and by contact with the skin.

Other Characteristics

Organic amides contain the structural group RCONH2 (where R is any organic radical). In some amides the hydrogen atoms are replaced by other R groups. Amides derive chemically from carboxylic acids by the replacement of the -OH portion of the grouping RCOOH with an -NH2 group. Imides contain the grouping (RCO)2NH. Most amides are solids at room temperature (exception: formamide). Amides containing five carbon atoms or fewer are soluble in water. Amides are versatile chemicals that enter into many useful reactions, especially in the fertilizer industry. Polyamides are polymers in which a succession of amide linkages link hold together a molecular chain of high molecular weight. Proteins in foods are naturally occurring polyamides; Nylon is a synthetic polymer.

Examples

Urea, acetamide, acrylamide, benzamide, caprolactam, formamide, dimethylformamide, phenylurea.

Reactivity Documentation

Click on the links below to see how this reactive group is predicted to react when it is mixed with one of the 47 reactive groups. A variety of documentation about that reactive group pair will be displayed, including predicted hazards, predicted gas byproducts, and background materials and references used to make the predictions.

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Amides and Imides, Organic

What are reactive groups?

Description

Reactivity Documentation